ArticleNature communications2026
Spatial and functional specialization of human splenic innate lymphoid cells.
Sarah J Colpitts, Sinthuja Jegatheeswaran, Siavash Mashhouri, Ash Hagerman, Mahmoud El-Maklizi, Humaira Murshed, Martin L Mak, Kyle T Reid, Julia M Murphy, Jessica A Mathews and 2 more
Abstract read
In one paragraphArticle in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
12 authors.
Sarah J ColpittsDepartment of Immunology, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Sinthuja JegatheeswaranDepartment of Immunology, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Siavash MashhouriDepartment of Immunology, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Ash HagermanDepartment of Immunology, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.ORCID 0000-0001-8417-7409 Mahmoud El-MakliziToronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada.ORCID 0000-0002-1229-5198 Humaira MurshedToronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada.
Martin L MakDepartment of Immunology, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Kyle T ReidDepartment of Immunology, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Julia M MurphyDepartment of Immunology, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.ORCID 0000-0002-0617-1666 Jessica A MathewsToronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada.ORCID 0000-0003-2926-8222 Clinton S RobbinsDepartment of Immunology, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.ORCID 0000-0001-9848-1495 Sarah Q CromeDepartment of Immunology, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada. scrome@bccrc.ca.ORCID 0000-0001-5117-7453 Funding
Canada Research Chairs (Chaires de recherche du Canada) 1026572Gouvernement du Canada | Natural Sciences and Engineering Research Council of Canada (Conseil de Recherches en Sciences Naturelles et en Génie du Canada) 512187
6 · The paper itselfAbstract
Secondary lymphoid organs, including the spleen, integrate innate and adaptive immune responses. Studies in murine models and humans highlight Natural Killer (NK) cells and other innate lymphoid cells (ILC) as key organizers of splenic immune activity, yet their in situ organization and interactions within immune networks are incompletely understood. Here, we report a spatially resolved single-cell atlas of human splenic NK cells and ILCs. We identify CD39
Indexed as
Immunity, InnateKiller Cells, NaturalLymphocytesSpleenAnimalsB-LymphocytesHumansMacrophages
Identifiers
PMID42711319
PMCPMC13554149
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