Evidence map›Paper›PMID 42711187›Full record

ArticleSleep health2026

Data-driven derivation of a multidimensional sleep health framework in adolescents.

Casandra C Nyhuis, Pura Ballester-Navarro, Susan L Calhoun, Jason Liao, Alexandros N Vgontzas, Edward O Bixler, Duanping Liao, Meredith L Wallace, Julio Fernandez-Mendoza

Abstract read
In one paragraph

Article in Sleep health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Casandra C NyhuisDepartment of Public Health Sciences, Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA; Sleep Research & Treatment Center, Department of Psychiatry, Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA.
Pura Ballester-NavarroDepartment of Pharmacy, Universidad Católica San Antonio de Murcia, Murcia, Spain.
Susan L CalhounSleep Research & Treatment Center, Department of Psychiatry, Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA.
Jason LiaoDepartment of Public Health Sciences, Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA.
Alexandros N VgontzasSleep Research & Treatment Center, Department of Psychiatry, Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA.
Edward O BixlerSleep Research & Treatment Center, Department of Psychiatry, Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA.
Duanping LiaoDepartment of Public Health Sciences, Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA.
Meredith L WallaceDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Julio Fernandez-MendozaSleep Research & Treatment Center, Department of Psychiatry, Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA. Electronic address: jfmendoza@psu.edu.

Funding

Penn State Clinical and Translational Science InstituteUL1TR002014 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI KRASCHNEWSKI, JENNIFER L. · 2016 to 2025
$33.7M
The Penn State Child Sleep Cohort: Cardiometabolic and Neurocognitive Risk in Young AdulthoodR01HL136587 · NHLBI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI FERNANDEZ-MENDOZA, JULIO · 2018 to 2022
$3.7M
NRSA Training CoreTL1TR002016 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI THOMAS, GAIL D. · 2016 to 2025
$3.4M
Sleep and cardio-metabolic risk factors: a prospective study of adolescentsR01HL097165 · NHLBI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI BIXLER, EDWARD O., LIAO, DUANPING · 2010 to 2013
$2.2M
PREVALENCE OF SLEEP DISORDERED BREATHING IN CHILDRENR01HL063772 · NHLBI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI BIXLER, EDWARD O. · 2001 to 2005
$1.3M
NCATS NIH HHS TL1 TR002016NCATS NIH HHS UL1 TR002014NHLBI NIH HHS R01 HL063772NHLBI NIH HHS R01 HL097165NHLBI NIH HHS R01 HL136587
6 · The paper itself

Abstract

objectivesMultidimensional sleep health captures the 24-hour experience of sleep as regularity, satisfaction, alertness, timing, efficiency, and duration. However, most evidence comes from adults. Adolescents have unique sleep needs that may not be fully represented. This study aimed to empirically identify and validate dimensions of adolescent sleep health and evaluate methods relevant to their assessment.

methodsWe analyzed subjective and objective sleep measures from 347 adolescents in the Penn State Child Cohort (16.3±2.2 years; 45.8% female; 22.2% race and ethnic minority). Exploratory factor analysis was conducted in a random 40% subsample to identify latent dimensions of self-reported, actigraphy, and polysomnography measures, followed by confirmatory factor analysis in the remaining 60% to test model validity.

resultsExploratory factor analysis identified 6 dimensions: Breathing, Efficiency, Duration, Regularity/variability, Satisfaction, and Timing, collectively referred to as the BEDReST framework, explaining 63% of the variance. Confirmatory factor analysis of individual factors within the 6-factor structure demonstrated good to excellent fit (Comparative Fit Index = 0.95-1.00; Tucker-Lewis Index = 0.86-1.00; Root Mean Square Error of Approximation = 0.06-0.15; Standardized Root Mean Square Residual < 0.08). All dimensions, except Satisfaction, included objective measures.

conclusionsWe empirically derived and validated 6 dimensions of adolescent sleep health, the BEDReST framework, using a multimethod approach. This approach highlighted the importance of including objective sleep data to comprehensively capture adolescent sleep health. The BEDReST framework extends existing models by incorporating sleep-disordered breathing and provides a foundation for refining the conceptualization and measurement of sleep health during adolescence.

Indexed as

ActigraphyAdolescenceFactor analysisMultidimensional sleep healthPolysomnographySubjective

Identifiers

PMID42711187
PMCPMC13555523

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.