Evidence map›Paper›PMID 42709975›Full record

ArticleDevelopmental medicine and child neurology2026

Immersive virtual reality arm exercise, physical activity, and cardiometabolic health in cerebral palsy: A phase 1 trial.

Byron Lai, Drew Davis, Raven Young, Ashley Wright, Robert A Oster, Huacong Wen, Erin Swanson-Kimani, Cynthia Wozow, Kelli Chaviano, Barbara Gower and 1 more

Abstract read
In one paragraph

Article in Developmental medicine and child neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Byron LaiDepartment of Pediatrics, Division of Pediatric Rehabilitation Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.ORCID https://orcid.org/0000-0002-5464-4720
Drew DavisDepartment of Pediatrics, Division of Pediatric Rehabilitation Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Raven YoungDepartment of Pediatrics, Division of Pediatric Rehabilitation Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Ashley WrightDepartment of Pediatrics, Division of Pediatric Rehabilitation Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Robert A OsterDepartment of Medicine, Division of General Internal Medicine and Population Science, University of Alabama at Birmingham, Birmingham, AL, USA.
Huacong WenDepartment of Physical Medicine and Rehabilitation, University of Alabama at Birmingham, Birmingham, AL, USA.
Erin Swanson-KimaniDepartment of Pediatrics, Division of Pediatric Rehabilitation Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Cynthia WozowDepartment of Pediatrics, Division of Pediatric Rehabilitation Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Kelli ChavianoDepartment of Pediatrics, Division of Pediatric Rehabilitation Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Barbara GowerDepartment of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL, USA.
James H RimmerSchool of Health Professions, Dean's Office, University of Alabama at Birmingham, Birmingham, AL, USA.

Funding

A PILOT TRIAL OF TELEHEALTH ACTIVE VIDEO GAMING USING IMMERSIVE VIRTUAL REALITY ON CARDIOMETABOLIC HEALTH AMONG YOUTH WITH CEREBRAL PALSYR03HD107598 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LAI, BYRON · 2022 to 2023
$294k
Eunice Kennedy Shriver National Institute of Child Health and Human Development R03HD107598NICHD NIH HHS R03 HD107598
6 · The paper itself

Abstract

aimTo examine the feasibility of a seated virtual reality exercise telehealth intervention on physical activity and cardiometabolic health in young people with cerebral palsy (CP).

methodThis was a randomized two-arm parallel group study: an immediate start group versus a waitlist control that continued usual activities of daily living. The home-based intervention targeted 150 minutes per week of moderate-intensity exergaming for 12 weeks, using Meta Quest virtual reality headsets and games, adapted for seated exercise. Data were collected remotely in weeks 0, 7, and 13.

resultsThirty-two young people with CP enrolled (mean age 16 years 8 months [SD 3 years 8 months], 19 females, 13 males), with a 9.4% dropout rate. Immediate start completers (n = 13) averaged 144 minutes per week (SD 73 minutes per week) of total exercise but fell short of the moderate-exercise target (150 minutes per week) at week 3 by 25%, week 6 by 31%, and week 12 by 48%. Immediate start surveys demonstrated that moderate-to-vigorous physical activity increased by 166% and 108% at weeks 7 and 13 respectively. Immediate start insulin levels improved by 45.2% and triglycerides by 20.2% from week 0 to 7. Waitlist control insulin and high-sensitivity C-reactive protein worsened from week 0 to 13 by 42.8% and 40% respectively.

interpretationSeated virtual reality exercise is a feasible and safe intervention that significantly increases physical activity participation. It shows potential for favorably influencing certain cardiometabolic markers, although further research is needed to establish sustained benefits.

Identifiers

PMID42709975
PMCPMC13632701

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.