ReviewScience progress
Bioactive coatings for biomedical engineering application: A review of mechanical integrity, biocompatibility, and future smart technologies.
Review in Science progress. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bioactive coatings have attracted considerable attention in the context of orthopedic and dental implantology, where establishing a stable and biologically active interface between the implant surface and surrounding hard tissue remains a central challenge. The present review examines the principal coating categories inorganic, organic, and hybrid with particular attention to their roles in promoting osseointegration, supporting bone regeneration, and reducing implant-associated infection in musculoskeletal and craniofacial applications. This review offers an in-depth examination of bioactive coatings, categorizing them into three main classes: inorganic, organic, and hybrid. It delves into their preparation techniques, characterization methods, and evaluation processes, detailing how these coatings are engineered and tested for optimal performance. Beyond the technical aspects, the review highlights several critical issues in the field, such as achieving long-term stability, preserving biofunctionality under physiological conditions, and enabling cost-effective scalability for broad application. Addressing these challenges could lead to significant progress, ranging from enhanced implant performance to reduced complications and improved patient outcomes. By overcoming existing limitations and integrating emerging technologies, bioactive coatings are well-positioned to play an important role in the future of medical device innovation and regenerative medicine, paving the way for more effective and personalized therapeutic solutions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.