ArticlePLoS neglected tropical diseases2026
A scoping review of the frequency and clinical presentation of Taenia solium taeniasis and human cysticercosis/neurocysticercosis in Papua, Indonesia from 1970 to 2024.
Article in PLoS neglected tropical diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTaenia solium taeniasis and cysticercosis, including neurocysticercosis (NCC), are neglected tropical diseases disproportionately affecting remote, resource-poor regions. As a leading cause of acquired epilepsy globally, T. solium poses a major public health challenge. METHODOLOGY/PRINCIPAL
findingsThis scoping review evaluated available literature on the prevalence of T. solium taeniasis and cysticercosis/NCC, clinical manifestations associated with infection, and diagnostic approaches used in Papua, Indonesia, from 1970 to 2024, following the PRISMA-ScR checklist. From 1,708 identified records, 28 articles underwent data extraction. Pooled prevalence estimates from studies conducted between 2007 and 2015 that used Enzyme-linked Immunoelectrotransfer Blot (EITB) indicated a taeniasis prevalence of 2.0% [95% CI: 1.0% - 6.0%] among household members in Central Papua and 3.0% [95% CI: 1.0% - 10.0%] in Highland Papua households. Furthermore, the pooled prevalence for residents in Central Papua positive by Enzyme-Linked Immunosorbent Assay (ELISA) for cysticercosis (studies from 1969-2015) was 5.0% [95% CI: 2.0% - 13.0%] compared to 29.0% [95% CI: 18.0% - 43.0%] in Highland Papua (studies from 1996-2011). Among 135 patients with headaches and/or seizures from both Central and Highland Papua (studies from 1998-2005), the pooled prevalence for ELISA-positive cysticercosis was 32.0% [95% CI: 9.0% - 69.0%]. Seizures were observed in 19.0% [95% CI: 12.0% - 28.0%] of villagers in Jayawijaya Regency that were ELISA positive for Taenia solium cysticercosis (studies from 1996-2001), with 35.0% [95% CI: 9.0% - 75.0%] presenting with subcutaneous nodules. Across all articles, only one study reported the use of brain computed tomography (CT) imaging for confirming NCC, indicating extremely limited access to neuroimaging in the region. CONCLUSIONS/SIGNIFICANCE: Improving access to gold-standard CT imaging for NCC diagnosis, adopting standardized criteria for NCC diagnosis and management, and targeted public health interventions are urgently needed to reduce the burden of T. solium in Papua.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.