Evidence map›Paper›PMID 42709848›Full record

ReviewJournal of speech, language, and hearing research : JSLHR2026

Lessons From the Communication Bridge Trials: Advancing Meaningful Dyadic Interventions Toward Implementation.

Emily Rogalski, Ollie Fegter, Alfred Rademaker, Matthew Bona, Angela C Roberts

Abstract readReview
In one paragraph

Review in Journal of speech, language, and hearing research : JSLHR, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Emily RogalskiHealthy Aging & Alzheimer's Research Care (HAARC) Center, Biological Sciences Division, University of Chicago, IL.ORCID 0000-0002-6472-1363
Ollie FegterHealthy Aging & Alzheimer's Research Care (HAARC) Center, Biological Sciences Division, University of Chicago, IL.ORCID 0000-0002-9023-4550
Alfred RademakerHealthy Aging & Alzheimer's Research Care (HAARC) Center, Biological Sciences Division, University of Chicago, IL.
Matthew BonaHealthy Aging & Alzheimer's Research Care (HAARC) Center, Biological Sciences Division, University of Chicago, IL.
Angela C RobertsDepartment of Computer Science, Western University, London, Ontario, Canada.ORCID 0000-0002-9226-8009

Funding

Communication Bridge: A person-centered Internet-based intervention for individuals with primary progressive aphasiaR56AG055425 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ROBERTS, ANGELA CHRISTINE, ROGALSKI, EMILY J · 2022 to 2022
$2.2M
Research Symposium in Communication Sciences and DisordersR13DC003383 · NIDCD · AMERICAN SPEECH-LANGUAGE-HEARING ASSN · PI MARGARET A. ROGERS · 1997 to 2026
$727k
NIA NIH HHS R56 AG055425NIDCD NIH HHS R13 DC003383
6 · The paper itself

Abstract

purposeThis review describes the historical motivations, development, and evolution of the Communication Bridge (CB) research program, which is designed to maximize quality of life and minimize burden for individuals living with dementia and their communication partners. The CB trials described comprise a series of dyadic, nonpharmacologic interventions supporting individuals with primary progressive aphasia (PPA) and their communication partners. Across trials, the CB intervention integrates speech-language, educational, and psychosocial approaches to maximize communication participation, confidence, and self-efficacy.

methodThe CB trials are contextualized within the National Institutes of Health (NIH) Stage Model for Behavioral Intervention Development and the Readiness Assessment for Pragmatic Trials (RAPT) framework to illustrate a systematic pathway from feasibility to implementation readiness. Three sequential telehealth-delivered trials are described: CB1, a pilot feasibility study; CB2, an international randomized controlled trial (RCT); and CB3, an ongoing international RCT designed with clinical practice-aligned procedures to advance readiness for future implementation testing.

resultsApplication of the NIH Stage Model and the RAPT framework highlights how staged intervention development can support rigor, reproducibility, and implementation readiness in behavioral intervention research for neurodegenerative conditions. Across trials, person-centered outcomes demonstrated meaningful benefit and maintenance over time, while iterative design refinements addressed feasibility, fidelity, acceptability, and scalability.

conclusionsThe CB research program illustrates how implementation science frameworks can be applied to advance meaningful, dyadic interventions for PPA toward real-world use. Lessons from early-phase trials underscore the importance of person-centered outcomes, staged rigor, and early attention to implementation considerations, with implications for future PPA intervention research and broader speech-language clinical trials.

Indexed as

Aphasia, Primary ProgressiveCommunicationDementiaHumansQuality of LifeUnited States

Identifiers

PMID42709848
PMCPMC13678536

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.