Evidence map›Paper›PMID 42709800›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

Negative feedback regulation of karrikin signaling in

Qingtian Li, Sun Hyun Chang, Andrew Tuckey, Claudia Sepulveda, Kartikye Varshney, Dan Li, Caroline Gutjahr, Mark T Waters, David C Nelson

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Qingtian Li *Department of Botany and Plant Sciences, University of California, Riverside, CA 92521.ORCID 0000-0001-5217-9813
Sun Hyun Chang *Department of Botany and Plant Sciences, University of California, Riverside, CA 92521.ORCID 0000-0001-6196-4098
Andrew TuckeySchool of Molecular Sciences, University of Western Australia, Perth, WA 6009, Australia.ORCID 0000-0003-3781-0608
Claudia SepulvedaDepartment of Botany and Plant Sciences, University of California, Riverside, CA 92521.ORCID 0000-0001-6044-9852
Kartikye VarshneyMax-Planck-Institut für Molekulare Pflanzenphysiologie, Potsdam-Golm 14476, Germany.
Dan LiYazhouwan National Laboratory, Sanya 572025, China.
Caroline GutjahrMax-Planck-Institut für Molekulare Pflanzenphysiologie, Potsdam-Golm 14476, Germany.ORCID 0000-0001-6163-745X
Mark T WatersSchool of Molecular Sciences, University of Western Australia, Perth, WA 6009, Australia.ORCID 0000-0001-5657-9005
David C NelsonDepartment of Botany and Plant Sciences, University of California, Riverside, CA 92521.ORCID 0000-0001-9792-5015

Funding

Department of Education and Training | Australian Research Council (ARC) DP210103078Department of Education and Training | Australian Research Council (ARC) DP240102441Deutsche Forschungsgemeinschaft (DFG) 491090170NSF (NSF) 1856741NSF (NSF) 2329271
6 · The paper itself

Abstract

Karrikins (KARs) are a class of butenolide molecules discovered in smoke hypothesized to mimic an undiscovered plant hormone, KAI2 ligand (KL). KAR/KL signaling regulates germination, seedling development, stress tolerance, and symbiotic interactions with soil microbes, among other traits. KAR/KL signaling is initiated by KARRIKIN INSENSITIVE2 (KAI2), an ɑ/β-hydrolase related to the strigolactone enzyme-receptor DWARF14 (D14). Activated KAI2 forms protein-protein interactions that trigger proteasomal degradation of a transcriptional regulator, SUPPRESSOR OF MAX2 1 (SMAX1), initiating changes in gene expression.

Indexed as

ArabidopsisArabidopsis ProteinsFuransPyransSignal TransductionFeedback, PhysiologicalGene Expression Regulation, PlantHydrolasesIntracellular Signaling Peptides and ProteinsNuclear ProteinsReceptors, Cell Surface3-methyl-2H-furo(2,3-c)pyran-2-oneArabidopsis ProteinsDWARF14 protein, ArabidopsisFuransHTL protein, ArabidopsisHydrolasesIntracellular Signaling Peptides and ProteinsNuclear ProteinsPyransReceptors, Cell SurfaceSMAX1 protein, Arabidopsisfeedbackkarrikinssignalingsynthetic enhancement

Identifiers

PMID42709800
PMCPMC13578778

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.