Evidence map›Paper›PMID 42709767›Full record

ArticlePloS one2026

Stakeholder-informed pre-implementation refinement of a pharmacy-led pre-exposure prophylaxis (PrEP) service delivery model in Malaysia.

Yan Nee Gan, Sin How Lim, Frederick L Altice, Sharifah Khadijah Syed Razif, Mariani Ahmad Nizaruddin, Reena Rajasuriar, Sazali Basri, Joselyn Pang, Andrew Yap, Iskandar Azwa and 1 more

Abstract read
In one paragraph

Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yan Nee GanDepartment of Social and Preventive Medicine, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.ORCID https://orcid.org/0000-0001-5558-243X
Sin How LimDepartment of Social and Preventive Medicine, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.
Frederick L AlticeCentre of Excellence for Research in Infectious Diseases and AIDS (CERiA), Universiti Malaya, Kuala Lumpur, Malaysia.ORCID https://orcid.org/0000-0002-7860-693X
Sharifah Khadijah Syed RazifCentre of Excellence for Research in Infectious Diseases and AIDS (CERiA), Universiti Malaya, Kuala Lumpur, Malaysia.
Mariani Ahmad NizaruddinDepartment of Community and Pharmacy Practice, Faculty of Pharmacy, University of Cyberjaya, Cyberjaya, Selangor, Malaysia.ORCID https://orcid.org/0000-0001-9528-5624
Reena RajasuriarCentre of Excellence for Research in Infectious Diseases and AIDS (CERiA), Universiti Malaya, Kuala Lumpur, Malaysia.
Sazali BasriCentre of Excellence for Research in Infectious Diseases and AIDS (CERiA), Universiti Malaya, Kuala Lumpur, Malaysia.ORCID https://orcid.org/0000-0002-5901-3864
Joselyn PangDepartment of Social and Preventive Medicine, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.
Andrew YapThe Red Clinic, Petaling Jaya, Selangor, Malaysia.
Iskandar AzwaCentre of Excellence for Research in Infectious Diseases and AIDS (CERiA), Universiti Malaya, Kuala Lumpur, Malaysia.
Rafdzah ZakiDepartment of Social and Preventive Medicine, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.

Funding

Malaysian Implementation Science Training (MIST) Program in HIVD43TW011324 · FIC · YALE UNIVERSITY · PI FREDERICK LEWIS ALTICE, Rafdzah Zaki · 2020 to 2026
$1.8M
FIC NIH HHS D43 TW011324
6 · The paper itself

Abstract

introductionIn 2024, only 3,451 individuals accessed free oral HIV pre-exposure prophylaxis (PrEP) at government clinics in Malaysia, despite an estimated 354,000 key population members who could benefit from PrEP. To inform pre-implementation refinement of a pharmacy-led PrEP service delivery model, we explored stakeholder perspectives on implementing the model within private community pharmacies in Malaysia. MATERIALS AND

methodsA one-day stakeholder consultation was conducted in April 2023 in Kuala Lumpur with 28 stakeholders representing community pharmacies, professional societies, telemedicine providers, non-governmental organizations (NGOs), and HIV implementation science researchers. The meeting began with a review of preliminary findings from formative qualitative research involving key populations, community pharmacists, and PrEP prescribers. Through facilitated discussions, stakeholders identified short- and long-term solutions to implementation barriers. Stakeholder inputs from discussions and structured worksheets were synthesized descriptively to identify recurring implementation considerations that informed refinement of the pilot model.

resultsKey implementation considerations included enhancing awareness and demand generation, ensuring privacy, confidentiality, and affordability, integrating HIV self-testing, using digital checklist-based assessments, simplifying laboratory testing requirements, developing practical workflows supported by a reference guide, strengthening pharmacist training, and fostering cross-sector collaboration. Identified training needs included PrEP fundamentals, eligibility assessment for initiation and continuation, referral procedures, and scenario-based learning. Key competencies included knowledge of HIV and sexually transmitted infections, risk assessment, professional conduct, and person-centered communication. Six study sites were selected, with preparation requirements including HIV self-test kits, PrEP medications, informational materials, trained pharmacists, telemedicine subscriptions, and nearby referral clinics. The consultation informed refinements to the implementation plan.

conclusionsThis stakeholder consultation informed refinement of a pharmacy-led PrEP service delivery model for pilot implementation in Malaysia and identified practical implementation considerations related to privacy, affordability, HIV self-testing, physician-pharmacist coordination, training, and referral systems. The findings may inform future implementation planning for similar urban, private-sector PrEP delivery models.

Indexed as

Anti-HIV AgentsCommunity Pharmacy ServicesHIV InfectionsPre-Exposure ProphylaxisStakeholder ParticipationHumansMalaysiaPharmaciesPharmacistsAnti-HIV Agents

Identifiers

PMID42709767
PMCPMC13552737

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.