Evidence map›Paper›PMID 42709360›Full record

ArticleEJNMMI physics2026

Toward an optimized PET reconstruction protocol for spinal cord: superiority of OSEM with TOF and PSF.

Jiyuan Wang, Jing Huang, Bixiao Cui, Hongwei Yang, Defeng Tian, Jie Ma, Wanru Duan, Zan Chen, Jie Lu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EJNMMI physics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jiyuan Wang *Department of Radiology and Nuclear Medicine, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing, 100053, China.
Jing Huang *Department of Radiology and Nuclear Medicine, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing, 100053, China.
Bixiao CuiDepartment of Radiology and Nuclear Medicine, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing, 100053, China.
Hongwei YangDepartment of Radiology and Nuclear Medicine, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing, 100053, China.
Defeng TianDepartment of Radiology and Nuclear Medicine, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing, 100053, China.
Jie MaDepartment of Radiology and Nuclear Medicine, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing, 100053, China.
Wanru DuanDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Zan ChenDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Jie LuDepartment of Radiology and Nuclear Medicine, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing, 100053, China. imaginglu@hotmail.com.ORCID http://orcid.org/0000-0003-0425-3921

Funding

Huizhi Ascent Project of Xuanwu Hospital HZ2021ZCLJ005
6 · The paper itself

Abstract

backgroundAlthough multiple PET reconstruction approaches have been successfully applied in brain and oncologic imaging, their performance in the context of spinal cord imaging remains unverified. This study aims to identify the optimal reconstruction method for spinal cord PET image analysis based on assessments of image quality and quantitative uptake.

methodsWe retrospectively analyzed

resultsThere were no significant differences in image noise among reconstruction methods (P > 0.05). Compared to OSEM reconstruction, the OSEM + PSF + TOF method significantly improved SNR (Z = 3.62, P < 0.01) and SBR (Z = 2.80, P = 0.03); the SBR of OSEM + PSF + TOF was also significantly higher than that of OSEM + PSF (Z = 3.04, P = 0.01). In large tumors, while image noise remained unaffected by the reconstruction method (P > 0.05), both SNR and SBR were significantly impacted (both P < 0.05). Specifically, OSEM + TOF + PSF achieved significantly higher SNR compared to OSEM (Z = 3.30, P < 0.01), and higher SBR compared to OSEM + PSF (Z = 3.14, P = 0.01). Quantitative lesion uptake metrics (SUV

conclusionThe OSEM + PSF + TOF reconstruction method demonstrated significant advantages in both image quality and quantitative assessment of FDG uptake, making it the recommended choice for spinal cord PET image reconstruction.

Indexed as

Hybrid PET/MRImage reconstructionPoint-spread functionSpinal cord tumorTime-of-flight

Identifiers

PMID42709360
PMCPMC13554005

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.