Evidence map›Paper›PMID 42709222›Full record

ArticleDie Naturwissenschaften2026

Metabolite profiling, enzyme inhibition, and in silico analysis of Commiphora gileadensis oleo-gum resin.

Hossam M Abdallah, Mohamed A Farag, Abdelsattar M Omar, Dina Abdulrahman I Albadawi, Gamal A Mohamed, Sabrin R M Ibrahim, Emad A AlSherif, Khaled A Mansour

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Article in Die Naturwissenschaften, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hossam M AbdallahDepartment of Natural Products and Alternative Medicine, Faculty of Pharmacy, King Abdulaziz University, Jeddah, 21589, Saudi Arabia. hmafifi@kau.edu.sa.
Mohamed A FaragPharmacognosy Department, Faculty of Pharmacy, Cairo University, Cairo, 11562, Egypt.
Abdelsattar M OmarDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.
Dina Abdulrahman I AlbadawiDepartment of Natural Products and Alternative Medicine, Faculty of Pharmacy, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.
Gamal A MohamedDepartment of Natural Products and Alternative Medicine, Faculty of Pharmacy, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.
Sabrin R M IbrahimDepartment of Chemistry, Preparatory Year Program, Batterjee Medical College, Jeddah, 21442, Saudi Arabia.
Emad A AlSherifDepartment of Botany and Microbiology, Faculty of Science, Beni-Suef University, Beni-Suef, 62511, Egypt.
Khaled A MansourPharmacognosy Department, Faculty of Pharmacy, Horus University in Egypt, New Damietta, 34517, Egypt.

Funding

king abulaziz university IPP-397-166-2025
6 · The paper itself

Abstract

Commiphora gileadensis oleo-gum resin is traditionally used in Arabia to manage diabetes, yet its phytochemical composition and mechanisms of action remain poorly characterized. To address this gap, an integrated UHPLC-MS/MS metabolomic strategy, in vitro enzyme inhibition, and in silico modeling were applied to characterize its constituents and evaluate its biological potential. UHPLC-MS/MS analysis led to the tentative annotation of fifty-five metabolites, expanding the known chemistry of this species. The ethanolic extract inhibited α-glucosidase (IC

Indexed as

CommiphoraEnzyme InhibitorsPlant ExtractsResins, Plantalpha-AmylasesChromatography, High Pressure LiquidComputer SimulationGlycoside Hydrolase InhibitorsHumansMetabolomicsMolecular Docking SimulationTandem Mass Spectrometryalpha-AmylasesEnzyme InhibitorsGlycoside Hydrolase InhibitorsPlant ExtractsResins, PlantCholinesteraseCommiphora gileadensisUHPLC–MS/MSα-amylaseα-glucosidase

Identifiers

PMID42709222

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.