Evidence map›Paper›PMID 42709183›Full record

ArticleAnalytical and bioanalytical chemistry2026

Nitrogen-doped carbon nanodots-based "off-on" fluorescent sensor for the detection of breast cancer-derived exosomes and early diagnosis.

Hongchao Tang, Yiling Chen, Jiangfeng Shang, Liquan Zhu, Jingyuan Xu, Chaoshen Wu, Yibing Zhou, Wenqian Xu, Xiaozhen Liu, Da Qian and 2 more

Abstract read
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In one paragraph

Article in Analytical and bioanalytical chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hongchao TangGeneral Surgery, Cancer Center, Department of Breast Surgery, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, 310014, China.
Yiling ChenSchool of Biology and Food Engineering, Suzhou University of Technology, Suzhou, 215500, China.
Jiangfeng ShangDepartment of Thyroid and Breast Surgery, Changshu Hospital Affiliated to Soochow University, Changshu No.1 People's Hospital, Changshu, 215500, China.
Liquan ZhuGeneral Surgery, Cancer Center, Department of Breast Surgery, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, 310014, China.
Jingyuan XuSchool of Biology and Food Engineering, Suzhou University of Technology, Suzhou, 215500, China.
Chaoshen WuCentral Laboratory, Department of Burn and Plastic Surgery-Hand Surgery, Changshu Hospital Affiliated to Soochow University, Changshu No.1 People's Hospital, Changshu, 215500, China.
Yibing ZhouCentral Laboratory, Department of Burn and Plastic Surgery-Hand Surgery, Changshu Hospital Affiliated to Soochow University, Changshu No.1 People's Hospital, Changshu, 215500, China.
Wenqian XuDepartment of Thyroid and Breast Surgery, Changshu Hospital Affiliated to Soochow University, Changshu No.1 People's Hospital, Changshu, 215500, China.
Xiaozhen LiuGeneral Surgery, Cancer Center, Department of Breast Surgery, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, 310014, China.
Da QianCentral Laboratory, Department of Burn and Plastic Surgery-Hand Surgery, Changshu Hospital Affiliated to Soochow University, Changshu No.1 People's Hospital, Changshu, 215500, China. qianda0215@suda.edu.cn.
Xuli MengGeneral Surgery, Cancer Center, Department of Breast Surgery, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, 310014, China. mxlmail@126.com.
Chaoqi HeGeneral Surgery, Cancer Center, Department of Breast Surgery, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, 310014, China. hechaoqi@hmc.edu.cn.

Funding

National Natural Science Foundation of China 82404685National Natural Science Foundation of China 82575061
6 · The paper itself

Abstract

Breast cancer is a leading cause of cancer death in women, requiring non-invasive early diagnostic tools. Exosomes are promising liquid biopsy biomarkers that reflect tumor-derived molecular information. Here, we developed an "off-on" fluorescent sensor using nitrogen-doped carbon nanodots (N-CNDs) for sensitive detection of breast cancer-derived exosomes. The sensor uses a magnetic bead-based aptamer complex (MBs-Apt-P1-P2) for target capture. P1 and P2 probes contain both EpCAM-recognition and Poly-T sequences. In the absence of targets, Ag

Indexed as

Breast cancerEarly diagnosisExosomesNitrogen-doped carbon nanodots“Off-on” fluorescent sensorSignal amplification

Identifiers

PMID42709183

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.