Evidence map›Paper›PMID 42708135›Full record

ArticleStroke (Hoboken, N.J.)2026

Flow Diversion for Anterior Communicating Artery Aneurysms: Systematic Review and Meta-Analysis.

Anderson Brito, William Davis Haselden, Leonardo Cruz-Criollo, Nashwa Abdelhakim, Jorge Cespedes, Edgar A Samaniego, Santiago Ortega-Gutierrez, Mario Zanaty

Abstract read
In one paragraph

Article in Stroke (Hoboken, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anderson BritoDepartment of Neurology (A.B., W.D.H., L.C.-C., N.A., J.C., E.A.S., S.O.-G.), University of Iowa Health Care, Iowa City.
William Davis HaseldenDepartment of Neurology (A.B., W.D.H., L.C.-C., N.A., J.C., E.A.S., S.O.-G.), University of Iowa Health Care, Iowa City.
Leonardo Cruz-CriolloDepartment of Neurology (A.B., W.D.H., L.C.-C., N.A., J.C., E.A.S., S.O.-G.), University of Iowa Health Care, Iowa City.ORCID https://orcid.org/0009-0007-6751-9463
Nashwa AbdelhakimDepartment of Neurology (A.B., W.D.H., L.C.-C., N.A., J.C., E.A.S., S.O.-G.), University of Iowa Health Care, Iowa City.ORCID https://orcid.org/0000-0003-4497-984X
Jorge CespedesDepartment of Neurology (A.B., W.D.H., L.C.-C., N.A., J.C., E.A.S., S.O.-G.), University of Iowa Health Care, Iowa City.ORCID https://orcid.org/0000-0001-9826-7077
Edgar A SamaniegoDepartment of Neurology (A.B., W.D.H., L.C.-C., N.A., J.C., E.A.S., S.O.-G.), University of Iowa Health Care, Iowa City.ORCID https://orcid.org/0000-0003-2764-2268
Santiago Ortega-GutierrezDepartment of Neurology (A.B., W.D.H., L.C.-C., N.A., J.C., E.A.S., S.O.-G.), University of Iowa Health Care, Iowa City.ORCID https://orcid.org/0000-0002-3408-1297
Mario ZanatyDepartment of Neurosurgery (E.A.S., S.O.-G., M.Z.), University of Iowa Health Care, Iowa City.ORCID https://orcid.org/0000-0002-6605-690X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnterior communicating artery (ACoA) aneurysms are associated with a higher risk of rupture. Flow diverters are considered a first-line treatment for intracranial aneurysms. However, the safety and efficacy of ACoA aneurysms are less established. This systematic review and meta-analysis aimed to evaluate the safety and effectiveness of flow diverters for ACoA aneurysms.

methodsWe conducted a systematic search from inception until June 2025. The primary effectiveness outcome was the complete occlusion rate at last follow-up, defined by the Raymond-Roy or O'Kelly-Marotta scales, and the primary safety outcome was mortality. Secondary safety outcomes included good functional outcome and major and minor neurological complications. Pooled estimates were calculated using a random-effects model. Subgroup analysis was performed based on follow-up time.

resultsFifteen studies were included (involving 350 patients with 358 ACoA aneurysms). The complete occlusion rate at last follow-up was 84.29% (95% CI, 79.36-88.22;

conclusionsOur results suggest that flow diverters could represent a potential treatment option for ACoA aneurysms, given the observed complete occlusion rate at last follow-up. However, larger prospective trials are required to further evaluate these findings.

Indexed as

flow diverterintracranial aneurysmmeta-analysis

Identifiers

PMID42708135
PMCPMC13549546

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.