Evidence map›Paper›PMID 42708088›Full record

ArticleSexual medicine2026

Psychological wellbeing of eunuchs and other individuals with interests in genital altering procedures.

Erik Wibowo, Thomas W Johnson, Jamie Agapoff

Abstract read
In one paragraph

Article in Sexual medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Erik WibowoSchool of Medical Sciences, Faculty of Medicine and Health, University of Sydney, Sydney 2006, Australia.ORCID https://orcid.org/0000-0002-5309-1490
Thomas W JohnsonDepartment of Anthropology (Emeritus), California State University, Chico, Chico, CA 95929, United States.ORCID https://orcid.org/0000-0002-2613-9217
Jamie AgapoffDepartment of Psychiatry, John A. Burns School of Medicine, University of Hawai'i at Manoa, Honolulu, HI 96813, United States.ORCID https://orcid.org/0000-0002-6026-6463

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The Eunuch Archive (EA) is an online community where individuals with interests in genital ablation share information, personal experiences, and social support. This study compared psychological wellbeing among individuals with different genital ablation interests and examined patterns and motivations for engaging with the EA. Methods: An anonymous online survey was posted on the EA website. Participants were categorized into 4 groups: individuals with genital ablation fantasies without a desire for surgery (Fantasy), individuals desiring orchiectomy but not having undergone the procedure (Aspiring), individuals who had undergone orchiectomy and were receiving androgen replacement therapy (Androgen Eunuchs), and individuals who had undergone orchiectomy without androgen replacement therapy (Eunuchs). Psychological wellbeing was assessed using validated measures of anxiety and depression (Hospital Anxiety and Depression Scale), insomnia (Insomnia Severity Index), and loneliness (Three-Item Loneliness Scale). Group differences were analyzed using ANOVA and chi-square tests, and regression analyses examined associations between reasons for visiting the EA and psychological outcomes. Results: The final sample included 338 participants (mean age 51.1 ± 15.7 years). Significant group differences were observed for loneliness and anxiety, but not for depression or insomnia. Individuals in the Eunuchs group reported lower loneliness and anxiety than participants in the Fantasy and Aspiring groups. Frequency of EA use was similar across groups, although motivations differed. Participants in the Fantasy group more frequently reported reading stories, whereas Aspiring individuals and Eunuchs more often sought medical information and social connection. Posting stories was associated with depressive symptoms (OR = 2.3, Discussion: Psychological wellbeing and motivations for engaging with the EA differed according to embodiment goals and surgical status. Individuals who had undergone orchiectomy without androgen replacement reported lower loneliness and anxiety than other groups. These findings highlight the importance of understanding online community engagement and psychosocial factors among individuals with genital ablation interests and may help clinicians provide more informed and non-stigmatizing care. Limitations include reliance on self-reported data from a single online community and the inability to verify participant responses.

Indexed as

eunuchEunuch Archivegenital ablationorchiectomypsychological wellbeing

Identifiers

PMID42708088
PMCPMC13549432

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.