Evidence map›Paper›PMID 42707938›Full record

ArticleERJ open research2026

Prevalence and associated factors of cough syncope in patients with chronic cough: a multicentre prospective study.

Jiung Jeong, Sujeong Kim, Han-Ki Park, Kyung Eun Park, Hwa Young Lee, Young-Chan Kim, Noeul Kang, Byung-Jae Lee, Seung-Eun Lee, Eun-Jung Jo and 11 more

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Article in ERJ open research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

21 authors.

Jiung JeongDepartment of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, South Korea.ORCID https://orcid.org/0000-0002-4726-7226
Sujeong KimDepartment of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, South Korea.ORCID https://orcid.org/0000-0002-2494-9216
Han-Ki ParkDepartment of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, South Korea.ORCID https://orcid.org/0000-0002-5460-9917
Kyung Eun ParkUniversity of Ulsan College of Medicine, Seoul, South Korea.ORCID https://orcid.org/0009-0006-3459-8508
Hwa Young LeeDivision of Allergy, Department of Internal Medicine, Seoul St Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
Young-Chan KimDepartment of Internal Medicine, Seoul National University Hospital, Seoul, South Korea.ORCID https://orcid.org/0000-0002-6726-5957
Noeul KangDivision of Allergy, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.ORCID https://orcid.org/0000-0003-0925-3891
Byung-Jae LeeDivision of Allergy, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
Seung-Eun LeeDepartment of Internal Medicine, Pusan National University Yangsan Hospital, Yangsan, South Korea.
Eun-Jung JoDepartment of Internal Medicine, School of Medicine, Pusan National University, Busan, South Korea.ORCID https://orcid.org/0000-0003-3712-6216
So Ri KimDivision of Respiratory Medicine and Allergy, Department of Internal Medicine, Jeonbuk National University Medical School, Jeonju, South Korea.ORCID https://orcid.org/0000-0002-6074-9158
Ha-Kyeong WonDepartment of Internal Medicine, Chungbuk National University College of Medicine, Chungbuk National University Hospital, Cheongju, South Korea.ORCID https://orcid.org/0000-0001-8127-7885
So-Young ParkDivision of Pulmonary, Allergy, and Critical Care Medicine, Department of Internal Medicine, Chung-Ang University, Gwangmyeong Hospital, Gwangmyeong, South Korea.
Sung-Yoon KangDepartment of Internal Medicine, Gachon University Gil Medical Center, Incheon, South Korea.
Sang-Heon KimDepartment of Internal Medicine, Hanyang University College of Medicine, Seoul, South Korea.ORCID https://orcid.org/0000-0001-8398-4444
Sae-Hoon KimDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, South Korea.
Yoon-Seok ChangDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, South Korea.ORCID https://orcid.org/0000-0003-3157-0447
Min-Hye ShinDepartment of Allergy and Clinical Immunology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
Woo-Jung SongDepartment of Allergy and Clinical Immunology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.ORCID https://orcid.org/0000-0002-4630-9922
Korean Chronic Cough Registry Investigators
Korean Chronic Cough Registry Investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cough syncope is a clinically significant complication of coughing, yet its epidemiology in patients with chronic cough remains poorly characterised. This study aimed to estimate the prevalence, and identify associated factors for cough syncope among patients with chronic cough. Methods: Data were analysed from the Korean Chronic Cough Registry, a multicentre prospective observational study. Adults with newly referred chronic cough were followed for 1 year. Cough syncope was defined based on patient self-report at enrolment and the 1-year follow-up visit. We compared clinical characteristics between patients with and without cough syncope and performed multivariable logistic regression to identify independent associated factors. Results: Among 682 eligible participants, cough syncope was identified in 13 (1.9%, 95% CI 1.0-3.2%). Patients with cough syncope were predominantly male (69.2% Conclusion: Cough syncope affects ∼2% of patients with chronic cough and is associated with male sex, obesity and refractory chronic cough, defining a distinct high-risk phenotype that warrants targeted risk stratification and prevention.

Identifiers

PMID42707938
PMCPMC13548435

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.