Evidence map›Paper›PMID 42707893›Full record

ArticleVirus evolution2026

Discovery of the order '

Alexander E Gorbalenya, Dmitry V Samborskiy, Benjamin W Neuman, Chris Lauber

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Virus evolution, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alexander E GorbalenyaLeiden University Center of Infectious Diseases, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, the Netherlands.ORCID https://orcid.org/0000-0002-4967-7341
Dmitry V SamborskiyBelozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Leninskie Gory 1, 119992 Moscow, Russia.ORCID https://orcid.org/0009-0004-1340-7165
Benjamin W NeumanDepartment of Biology, Microbial Pathogenesis & Immunity, Texas A&M University, 525 Lubbock St, College Station, TX 77843,  United States.
Chris LauberInstitute for Experimental Virology, TWINCORE Centre for Experimental and Clinical Infection Research, a joint venture between the Hannover Medical School (MHH) and the Helmholtz Centre for Infection Research (HZI), Feodor-Lynen-Str. 7, 30625 Feodor-Lynen-Str. 7, 30625 Hannover, Germany.ORCID https://orcid.org/0000-0002-2265-2953

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genome replication in positive-stranded RNA (ssRNA+) viruses is mediated by cognate enzymes, including ubiquitous RNA-dependent RNA polymerase (RdRp). In ssRNA+ viruses with multiple open reading frames (ORFs) in their genomes, replication often is accompanied by synthesis of subgenomic RNAs (transcription) for expression of 3'-proximal ORFs. In addition, all ssRNA+ viruses with genomes larger than ~7 kb encode helicases, linking helicases to RNA genome expansion. Helicases are essential ATPases that unwind nucleic acids and are classified into six recognized superfamilies (SF1-SF6). In the phylum

Indexed as

AAA+/RecA-like ATPasediscontinuous transcriptionhelicase superfamilynidovirus evolutionQuisviralesRNA virus replicase

Identifiers

PMID42707893
PMCPMC13548321

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.