Evidence map›Paper›PMID 42707713›Full record

ArticleDrug design, development and therapy2026

Assessment of the Cytotoxic and Apoptotic Impacts of Bimetallic Zinc Iron Oxide Nanoparticles on HuH-7 Cell Line.

Nawal M Al-Malahi, Daoud Ali, Jawaher Alzahrani, Saad Alkahtani, Bader O Almutairi, Saud Alarifi

Abstract read
In one paragraph

Article in Drug design, development and therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nawal M Al-MalahiDepartment of Zoology, College of Science, King Saud University, Riyadh, 11451, Saudi Arabia.
Daoud AliDepartment of Zoology, College of Science, King Saud University, Riyadh, 11451, Saudi Arabia.ORCID 0000-0002-1045-4984
Jawaher AlzahraniDepartment of Zoology, College of Science, King Saud University, Riyadh, 11451, Saudi Arabia.
Saad AlkahtaniDepartment of Zoology, College of Science, King Saud University, Riyadh, 11451, Saudi Arabia.ORCID 0000-0001-7381-5110
Bader O AlmutairiDepartment of Zoology, College of Science, King Saud University, Riyadh, 11451, Saudi Arabia.ORCID 0000-0002-4697-5204
Saud AlarifiDepartment of Zoology, College of Science, King Saud University, Riyadh, 11451, Saudi Arabia.ORCID 0000-0002-3613-5228

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Observation: One of the main causes of death worldwide is hepatic carcinoma, which is resistant to several anticancer drugs. This work investigated the cytotoxic effects of bimetallic zinc iron oxide ZnFe Methods: Before being exposed to target cell line, ZnFe Results: The median inhibitory concentration (IC Conclusion: The aforementioned findings point out the significance of ZnFe

Indexed as

Antineoplastic AgentsApoptosisFerric CompoundsLiver NeoplasmsMetal NanoparticlesZincCell Line, TumorCell ProliferationCell SurvivalDose-Response Relationship, DrugDrug Screening Assays, AntitumorHumansMembrane Potential, MitochondrialParticle SizeReactive Oxygen SpeciesStructure-Activity RelationshipAntineoplastic AgentsFerric Compoundsferric oxideReactive Oxygen SpeciesZincapoptosisHuH-7 cell lineMTT assayROSZnFe2O4NPs

Identifiers

PMID42707713
PMCPMC13549323

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.