Evidence map›Paper›PMID 42707632›Full record

ArticleNeuro-oncology advances

Pattern of care and treatment outcome of high-grade glioma patients at 4 Ethiopian teaching hospitals: a prospective cohort study.

Dawit Workneh Gechu, Tsegazeab Laeke Tekelemariam, Bethelhem Yesehak Worku, Mehari Wale Alem, Yordanose Girma Legesse

Abstract read
In one paragraph

Article in Neuro-oncology advances. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dawit Workneh GechuNeurosurgery Unit, Department of Surgery, University of Gondar, Gondar, Ethiopia.ORCID https://orcid.org/0000-0002-7357-6305
Tsegazeab Laeke TekelemariamNeurosurgery Unit, Department of Surgery, Addis Ababa University, Addis Ababa, Ethiopia.ORCID https://orcid.org/0000-0003-4287-1413
Bethelhem Yesehak WorkuNeurosurgery Unit, Department of Surgery, Addis Ababa University, Addis Ababa, Ethiopia.ORCID https://orcid.org/0000-0001-8656-6379
Mehari Wale AlemDepartment of Neurosurgery, Saint Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.ORCID https://orcid.org/0009-0000-2148-6175
Yordanose Girma LegesseAletha Medical Center, Addis Ababa, Ethiopia.ORCID https://orcid.org/0009-0005-2238-5401

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: High-grade gliomas are the most prevalent type of malignant brain tumor in adults and the second leading cause of cancer-related death. This study assesses epidemiology, pattern of care, and treatment outcome of high-grade glioma in Ethiopia. Methods: A Prospective cohort study. Data collected were analyzed using SPSS. Frequency distribution was used to describe the characteristics of the study participants. Chi-squared tests and survival analysis were used to assess the treatment outcomes. Variables with Results: There was a total of 40 patients. The median age at diagnosis was 47 years. Headache was the commonest presenting symptom (97.5%), followed by seizure (52.5%) and weakness (50%). The pre-operative tumor volume ranged between 3.9 and 168 cm Conclusion: In our study, the mean survival time was 20.77 months. Higher KPS, pre-operative Glasgow Coma Scale (GCS) of 15, and patients receiving post-op adjuvant therapy had a significant favorable association with survival in our study.

Indexed as

brain tumorGBMhigh grade gliomaLMIC

Identifiers

PMID42707632
PMCPMC13548784

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.