Evidence map›Paper›PMID 42707580›Full record

ReviewFrontiers in cell and developmental biology2026

The cornea-trigeminal axis: potassium channels as master regulators of ocular surface homeostasis and sensory transduction.

Jiali Zhang, Xinyi Chen, Jing Ji, Pengfan Chen, Jiaxin Yao, Longqian Liu, Li Tang, Xiangyi Wen

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in cell and developmental biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jiali ZhangDepartment of Ophthalmology, Department of Optometry and Visual Science, Laboratory of Optometry and Vision Sciences, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Xinyi ChenWest China School of Medicine, Sichuan University, Chengdu, Sichuan, China.
Jing JiDepartment of Ophthalmology, Department of Optometry and Visual Science, Laboratory of Optometry and Vision Sciences, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Pengfan ChenDepartment of Ophthalmology, Department of Optometry and Visual Science, Laboratory of Optometry and Vision Sciences, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Jiaxin YaoDepartment of Ophthalmology, Department of Optometry and Visual Science, Laboratory of Optometry and Vision Sciences, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Longqian LiuDepartment of Ophthalmology, Department of Optometry and Visual Science, Laboratory of Optometry and Vision Sciences, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Li TangDepartment of Ophthalmology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Xiangyi WenDepartment of Ophthalmology, Department of Optometry and Visual Science, Laboratory of Optometry and Vision Sciences, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The cornea and trigeminal ganglion (TG) form an integrated sensory network that monitors ocular surface integrity and mediates protective responses to environmental stimuli. Potassium (K Methods: This review synthesizes current knowledge of K Results: In corneal epithelial and stromal cells, channels such as Kir4.1 and K Discussion: Despite advances in animal and

Indexed as

corneadry eye diseaseneuropathic painpotassium channelssensory transductiontrigeminal ganglion

Identifiers

PMID42707580
PMCPMC13547729

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.