ArticleFrontiers in public health2026
Epidemiological characteristics of leptospirosis and serological surveillance among reservoir animals and healthy populations in Fujian, China, 2004-2024.
Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Leptospirosis is a globally distributed zoonosis caused by pathogenic Methods: Data on human leptospirosis cases, reservoir animals, and healthy populations in Fujian Province from 2004 to 2024 were collected through the Infectious Disease Surveillance System of the Chinese Center for Disease Control and Prevention and 31 surveillance sites. Descriptive epidemiological methods were used to analyze temporal, spatial, and population distribution characteristics. Joinpoint regression, spatial autocorrelation, and spatiotemporal scan analyses were performed to identify temporal trends and spatiotemporal clustering. Serological data from rodents and healthy populations were analyzed to assess antibody prevalence and serogroup distribution. Results: From 2004 to 2024, the incidence of leptospirosis in Fujian Province showed a significant downward trend, with an average annual incidence of 0.08 cases per 100,000 population. A total of 681 cases were reported, mainly between July and October and concentrated in northern and north-central Fujian. Farmers and individuals aged 30-69 years constituted the major affected populations, and the age at onset gradually increased over time. Significant spatial clustering was observed (Moran's Conclusion: Leptospirosis incidence in Fujian Province declined substantially from 2004 to 2024 but remained characterized by marked spatial clustering and seasonal patterns. Rodents remained important reservoir hosts of
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