Evidence map›Paper›PMID 42707410›Full record

ArticleFrontiers in public health2026

Safety and quality of public chatbots for lung cancer prognostic information: a comparative evaluation.

Yanru Jiang, Qianyun Wang, Liang Zheng, Lei Zhang, Bo Jiang, Jingjuan Xu, Jun Wang, Jiaying Zhu, Zhishui Wu

Abstract readComparative Study
In one paragraph

Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Yanru JiangDepartment of Thoracic Surgery, The First People's Hospital of Changzhou, Changzhou, Jiangsu, China.
Qianyun WangDepartment of Thoracic Surgery, The First People's Hospital of Changzhou, Changzhou, Jiangsu, China.
Liang ZhengDepartment of Thoracic Surgery, The First People's Hospital of Changzhou, Changzhou, Jiangsu, China.
Lei ZhangDepartment of Thoracic Surgery, The First People's Hospital of Changzhou, Changzhou, Jiangsu, China.
Bo JiangDepartment of Thoracic Surgery, The First People's Hospital of Changzhou, Changzhou, Jiangsu, China.
Jingjuan XuDepartment of Thoracic Surgery, The First People's Hospital of Changzhou, Changzhou, Jiangsu, China.
Jun WangDepartment of Thoracic Surgery, The First People's Hospital of Changzhou, Changzhou, Jiangsu, China.
Jiaying ZhuDepartment of Thoracic Surgery, The First People's Hospital of Changzhou, Changzhou, Jiangsu, China.
Zhishui WuDepartment of Thoracic Surgery, The First People's Hospital of Changzhou, Changzhou, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To compare the safety, accuracy, empathy, reliability, information quality, and readability of five publicly accessible large language model chatbots when answering patient-facing lung cancer prognostic questions under standardized single-turn English prompting. Methods: In this Chatbot Health Advice Reporting Transparency-guided cross-sectional evaluation, 53 standardized English prompts were submitted once to ChatGPT, Gemini, Copilot, DeepSeek, and Doubao through official web interfaces during April 1-21, 2026. Five blinded raters assessed 265 responses for safety, accuracy, empathy, DISCERN, EQIP, JAMA benchmark criteria, Global Quality Scale, and readability. Paired repeated-measures analyses were used. Results: Inter-rater agreement was good to excellent. Safety differed significantly across models (Cochran's Q = 14.089, df = 4, Conclusion: Public-facing chatbots differed substantially in safety, reliability, communication quality, and readability. These findings are time-, interface-, and prompt-dependent. Chatbots may support general patient education but should not replace individualized clinician-led prognostic communication.

Indexed as

Lung NeoplasmsComprehensionCross-Sectional StudiesHumansInternetLarge Language ModelsPrognosisReproducibility of Resultsempathygenerative AI chatbotslarge language modelslung cancerprognostic informationreadabilityreliabilitysafety

Identifiers

PMID42707410
PMCPMC13547269

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.