Evidence map›Paper›PMID 42707237›Full record

ArticleFrontiers in neurology2026

Impact of migraine on quality of life and disability: a matched cross-sectional comparative study in a tertiary hospital in Malaysia.

Firyal Harlina Hussain, Juen Kiem Tan, Rathika Rajah, Ching Soong Khoo, Wan Nur Nafisah Wan Yahya, Rabani Remli, Michelle Maryanne Tan, Rosnah Sutan, Hui Jan Tan

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

9 authors.

Firyal Harlina HussainDepartment of Medicine, Faculty of Medicine, the National University of Malaysia, Kuala Lumpur, Malaysia.
Juen Kiem TanDepartment of Medicine, Faculty of Medicine, the National University of Malaysia, Kuala Lumpur, Malaysia.
Rathika RajahDepartment of Medicine, Faculty of Medicine, the National University of Malaysia, Kuala Lumpur, Malaysia.
Ching Soong KhooDepartment of Medicine, Faculty of Medicine, the National University of Malaysia, Kuala Lumpur, Malaysia.
Wan Nur Nafisah Wan YahyaDepartment of Medicine, Faculty of Medicine, the National University of Malaysia, Kuala Lumpur, Malaysia.
Rabani RemliDepartment of Medicine, Faculty of Medicine, the National University of Malaysia, Kuala Lumpur, Malaysia.
Michelle Maryanne TanDepartment of Medicine, Hospital Tengku Ampuan Rahimah, Klang, Selangor, Malaysia.
Rosnah SutanDepartment of Medicine, Hospital Canselor Tuanku Muhriz, Kuala Lumpur, Malaysia.
Hui Jan TanDepartment of Medicine, Faculty of Medicine, the National University of Malaysia, Kuala Lumpur, Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Migraine-related disabilities have a significant disease burden and are an important factor in impaired quality of life (QOL) of affected persons. This study aimed to compare QOL and migraine disability score in patients with migraine with healthy controls. Methods: A matched cross-sectional comparative study was carried out at the Neurology Clinic between August 2023 and March 2026. The study population included 100 migraine patients aged 18-60 years and 100 healthy controls matched by age and sex. All participants completed the World Health Organization Quality of Life Brief (WHOQOL-BREF) questionnaire, and migraine patients completed the Migraine Disability Assessment (MIDAS). Results: A total of 100 migraine patients and 100 controls were recruited. Participants with migraine had a significantly lower total WHOQOL-BREF score than controls ( Conclusion: Migraines are associated with a significant decrease in QOL and increased disability, especially in physical health. These findings highlight the burden of migraine on daily function and wellbeing. Using these validated assessment tools to evaluate quality of life and detect disabilities, clinicians can facilitate more effective and individualized management plans.

Indexed as

Migraine DisordersPersons with DisabilitiesQuality of LifeAdolescentAdultCross-Sectional StudiesDisability EvaluationFemaleHumansMalaysiaMaleMiddle AgedSurveys and QuestionnairesTertiary Care CentersYoung AdultMIDASmigrainemigraine disabilityquality of lifeWHOQOL-BREF

Identifiers

PMID42707237
PMCPMC13547049

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.