Evidence map›Paper›PMID 42706958›Full record

Observational studyPediatrics international : official journal of the Japan Pediatric Society

Outcomes and Regional Care Patterns of Critically Ill Pediatric Emergency Patients: A Population-Based Registry Study.

Noriyuki Kaku, Kanako Higashi, Go Kawano, Masashi Kobayashi, Jun Muneuchi, Shinichi Morimoto, Kenji Furuno, Junpei Mukai, Jun Kono, Wakato Matsuoka and 4 more

Abstract readObservational Study
In one paragraph

Observational study in Pediatrics international : official journal of the Japan Pediatric Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Noriyuki KakuDepartment of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.ORCID https://orcid.org/0000-0001-6803-4635
Kanako HigashiDepartment of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.ORCID https://orcid.org/0009-0000-0349-186X
Go KawanoDepartment of Pediatrics, St. Mary's Hospital, Kurume, Japan.
Masashi KobayashiDepartment of Pediatrics, Kitakyushu City Yahata Hospital, Kitakyushu, Japan.ORCID https://orcid.org/0000-0002-3899-4966
Jun MuneuchiDepartment of Pediatrics, Kyushu Hospital, Japan Community Healthcare Organization, Kitakyushu, Japan.ORCID https://orcid.org/0000-0003-0500-2585
Shinichi MorimotoDepartment of Emergency and Critical Care Medicine, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.ORCID https://orcid.org/0000-0002-3012-1941
Kenji FurunoDepartment of General Pediatrics & Interdisciplinary Medicine, Fukuoka Children's Hospital, Fukuoka, Japan.ORCID https://orcid.org/0000-0003-3991-8348
Junpei MukaiDepartment of Pediatrics and Child Health, Kurume University School of Medicine, Kurume, Japan.
Jun KonoEmergency and Critical Care Center, Kyushu University Hospital, Fukuoka, Japan.
Wakato MatsuokaDepartment of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.ORCID https://orcid.org/0000-0002-4446-4929
Soichi MizuguchiDepartment of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.ORCID https://orcid.org/0000-0002-6211-8640
Kenichiro YamamuraDepartment of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.ORCID https://orcid.org/0000-0002-5684-1330
Yasunari SakaiDepartment of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.ORCID https://orcid.org/0000-0002-5747-8692
Tomohiko AkahoshiDepartment of Advanced Emergency and Disaster Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.ORCID https://orcid.org/0000-0002-1750-2299

Funding

Japan Society for the Promotion of Science (JSPS) JP23K15618Japan Society for the Promotion of Science (JSPS) JP24K13391Japan Society for the Promotion of Science (JSPS) JP25K14454
6 · The paper itself

Abstract

backgroundClarifying clinical features of critically ill pediatric patients is essential for optimizing the regional emergency care system. However, the relationships between hospital case volume, interhospital transfer, and outcomes, including causes of death, remain unclear.

methodsAn observational study was conducted using prospectively collected data on critically ill patients aged 15 years or younger. Patients enrolled in this study were those who met the criteria for emergency and critical care unit management in Fukuoka Prefecture, Japan, from June 2014 to May 2019. Data on etiologic categories, outcomes, interhospital transfer, and use of intensive care interventions were collected. Hospitals were classified according to patient volume (high-volume: ≥ 100 and low-volume: < 100 patients during the observation period).

resultsAmong 3124 patients, 891 (28.5%) were infants (< 1 year). The annual incidence was 0.85 per 1000 children. Endogenous, exogenous, and "undetermined" etiologies accounted for 2481 (79.4%), 495 (15.8%), and 148 (4.7%) patients, respectively. Of 327 deaths (10.5%), 157 (48.0%) occurred in infants, and 89 (56.7%) of infant deaths were classified as "undetermined". In-hospital mortality among admitted patients was higher in low-volume hospitals (8.7% vs. 5.3%, p < 0.01), as was the proportion of "undetermined" deaths (49.5% vs. 28.8%, p < 0.01). Transferred patients had higher ICU admission rates (62.5% vs. 52.6%, p < 0.01), without higher mortality among admitted patients.

conclusionsCritically ill infants had high mortality, and many deaths remained undetermined. These findings highlight the need to strengthen regional transport systems and postmortem evaluation in pediatric emergency care.

Indexed as

Critical CareCritical IllnessAdolescentChildChild, PreschoolFemaleHospital MortalityHumansIncidenceInfantInfant, NewbornJapanMalePatient TransferProspective StudiesRegistrieschild death reviewcritically ill childrenepidemiologyhospital case volumepediatric emergency care

Identifiers

PMID42706958
PMCPMC13551226

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.