Evidence map›Paper›PMID 42706756›Full record

ArticleAmerican journal of human biology : the official journal of the Human Biology Council2026

Direct and Indirect Effects of Adolescent Motherhood on Under-Five Mortality in Pakistan: Evidence From a Nationally Representative Survey.

Naeem Rabbani, Zhongliang Zhou, Rashed Nawaz, Neelum Khalid

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Article in American journal of human biology : the official journal of the Human Biology Council, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Naeem RabbaniSchool of Public Policy and Administration, Xi'an Jiaotong University, Xi'an, China.
Zhongliang ZhouSchool of Public Policy and Administration, Xi'an Jiaotong University, Xi'an, China.ORCID https://orcid.org/0000-0002-3850-4752
Rashed NawazSchool of Public Health and Health Nutrition, Luohe Medical College, Luohe, Henan, China.ORCID https://orcid.org/0009-0001-1818-1749
Neelum KhalidSchool of Public Policy and Administration, Xi'an Jiaotong University, Xi'an, China.ORCID https://orcid.org/0009-0001-0476-6420

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdolescent motherhood is associated with adverse child survival outcomes, particularly in low- and middle-income settings. Maternal and child health (MCH) service utilization may represent an important pathway linking adolescent motherhood with child survival, but evidence from Pakistan remains limited. This study examined the association between adolescent motherhood and under-five mortality and assessed the statistical indirect association through MCH service utilization.

methodsWe analyzed nationally representative data from the 2018 Pakistan Demographic and Health Survey, including 8159 mother-child observations. Under-five mortality was examined as a time-to-event outcome. We used multivariable generalized structural equation modeling with a Weibull proportional hazards specification to estimate associations between adolescent motherhood, MCH service utilization, and under-five mortality. We constructed the MCH service utilization index from indicators of antenatal care, skilled delivery care, and postnatal care. Indirect associations were evaluated using 5000 bootstrap replications and 95% bias-corrected bootstrap confidence intervals. All analyses were conducted using STATA version 17.1.

resultsOverall, 4.09% of children died before age five, and 37.55% were born to adolescent mothers. After adjustment for prespecified covariates, adolescent motherhood was associated with higher under-five mortality (HR = 2.05, p < 0.001) and lower MCH service utilization (β = -0.02, p = 0.044). Higher MCH service utilization was associated with lower under-five mortality (HR = 0.26, p < 0.001). After accounting for MCH service utilization, adolescent motherhood remained associated with higher under-five mortality (HR = 1.99, p < 0.001). The indirect association through MCH service utilization was positive and statistically supported (β = 0.0223; bootstrap SE = 0.0103; 95% [BCCI: 0.0038-0.0398]).

conclusionAdolescent motherhood was associated with higher under-five mortality and lower MCH service utilization, while greater MCH service utilization was associated with lower under-five mortality. The findings suggest that differences in MCH service utilization account for part of the observed association between adolescent motherhood and under-five mortality. Improving access to and utilization of MCH services, alongside interventions addressing adolescent pregnancy and broader social determinants of child health, may contribute to improved child survival in Pakistan.

Indexed as

Adolescent MothersChild MortalityFacilities and Services UtilizationMaternal-Child Health ServicesAdolescentChild, PreschoolDemographyFemaleHumansInfantInfant, NewbornLatent Class AnalysisMalePakistanPregnancy in Adolescenceadolescent motherhoodmaternal and child health servicesPakistanunder‐five mortality

Identifiers

PMID42706756
PMCPMC13550953

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.