Evidence map›Paper›PMID 42706747›Full record

ReviewGlobal spine journal2026

Longitudinal Evidence on Natural History, Nonoperative Management, and Multimodal Surveillance in Mild to Moderate Degenerative Cervical Myelopathy: A Scoping Review.

Bo Xu, Dong-Sheng Yuan, Ya-Ling Gao, Guo-Liang Ma, Zhi-Zhuang Wang, Yan-Zhen Zhang, Xin Chen, Bo-Wen Yang, Xiao-Kuan Qin, Peng-Hui Li and 5 more

Abstract readReview
In one paragraph

Review in Global spine journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Bo XuDepartment of Spine, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China.ORCID 0000-0003-2280-9495
Dong-Sheng YuanDepartment of Spine, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China.ORCID 0009-0003-4001-0692
Ya-Ling GaoDepartment of Spine, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Guo-Liang MaDepartment of Spine, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Zhi-Zhuang WangDepartment of Spine, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Yan-Zhen ZhangDepartment of Spine, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Xin ChenDepartment of Spine, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Bo-Wen YangDepartment of Spine, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Xiao-Kuan QinDepartment of Spine, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Peng-Hui LiDepartment of Spine, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Ke-Xin YangDepartment of Spine, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Jie YuDepartment of Spine, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Li-Guo ZhuDepartment of Spine, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Min-Shan FengDepartment of Spine, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
He YinDepartment of Spine, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China.ORCID 0000-0003-2055-3270

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Study DesignScoping review.ObjectivesTo map longitudinal evidence on natural history, nonoperative management, progression definitions, clinical decision variables, and multimodal surveillance in mild to moderate degenerative cervical myelopathy (DCM), while distinguishing the treatment implications of mild and moderate disease.MethodsPubMed/MEDLINE, Embase, Web of Science Core Collection, Scopus, and the Cochrane Library were searched from inception to March 22, 2026. The review followed PRISMA-ScR. Eligible studies were adult longitudinal reports of mild or moderate DCM/cervical spondylotic myelopathy, extractable mild/moderate subgroups, or clinically relevant progression-surveillance evidence. Data were charted for design, population, management, follow-up, endpoints, progression definitions, examination findings, imaging variables, CT-relevant pathology, and alignment or motion factors.ResultsOf 6,193 records, 4,137 remained after deduplication and 766 underwent full-text consideration. Thirty-two reports underwent final eligibility assessment; 28 were retained, including 13 main analytic studies, 7 supplementary or conditional studies, and 8 adjunct multimodal narrative studies. Evidence was heterogeneous in severity thresholds, progression definitions, endpoints, and follow-up schedules. Nonoperative and natural-history cohorts showed that mild to moderate disease is not uniformly stable; some patients remained stable, whereas others deteriorated or crossed over to surgery. Objective function, quantitative MRI, electrophysiology, and selected structural measures may detect change more sensitively than symptom scales or conventional MRI alone.ConclusionsMild to moderate DCM represents a surveillance population, but mild and moderate disease should not be treated as having identical indications. Nonoperative cohorts help define progression and escalation risk, and multimodal follow-up appears more informative than single-scale monitoring.

Indexed as

cervical spondylotic myelopathydegenerative cervical myelopathymild to moderate diseasenatural historyscoping review

Identifiers

PMID42706747
PMCPMC13553986

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.