Evidence map›Paper›PMID 42706523›Full record

ArticleBMC pulmonary medicine2026

Moving beyond treatment: pulmonary function, autonomous motivation, and physical activity enjoyment in adults with cystic fibrosis.

Wolfgang Gruber, Matthias Welsner, Florian Stehling, Jin-Sun Schermaul, Jose G Ortiz, Liron Lechtenberg, Christian Taube, Margarete Olivier

Abstract read
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In one paragraph

Article in BMC pulmonary medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wolfgang GruberPaediatric Pulmonology and Sleep Medicine, Cystic Fibrosis Centre, Children´S Hospital, University of Duisburg-Essen, 45147, Essen, Germany. wolfgang.gruber@uk-essen.de.ORCID https://orcid.org/0000-0003-2186-9269
Matthias WelsnerDepartment of Pulmonary Medicine, Adult Cystic Fibrosis Center, University Hospital Essen - Ruhrlandklinik, University of Duisburg-Essen, Essen, Germany.
Florian StehlingPaediatric Pulmonology and Sleep Medicine, Cystic Fibrosis Centre, Children´S Hospital, University of Duisburg-Essen, 45147, Essen, Germany.
Jin-Sun SchermaulDepartment of Pulmonary Medicine, Adult Cystic Fibrosis Center, University Hospital Essen - Ruhrlandklinik, University of Duisburg-Essen, Essen, Germany.
Jose G OrtizDepartment of Pulmonary Medicine, Adult Cystic Fibrosis Center, University Hospital Essen - Ruhrlandklinik, University of Duisburg-Essen, Essen, Germany.
Liron LechtenbergDepartment of Pulmonary Medicine, Adult Cystic Fibrosis Center, University Hospital Essen - Ruhrlandklinik, University of Duisburg-Essen, Essen, Germany.
Christian TaubeDepartment of Pulmonary Medicine, Adult Cystic Fibrosis Center, University Hospital Essen - Ruhrlandklinik, University of Duisburg-Essen, Essen, Germany.
Margarete OlivierPaediatric Pulmonology and Sleep Medicine, Cystic Fibrosis Centre, Children´S Hospital, University of Duisburg-Essen, 45147, Essen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPhysical activity (PA) and structured exercise are established cornerstones of cystic fibrosis (CF) management. While CFTR modulators have transformed treatment, the psychological factors affecting sustained PA adherence, particularly motivational regulation and PA enjoyment, require further investigation. This study aimed to determine whether percent predicted forced expiratory volume in one second (ppFEV₁) is independently associated with autonomous motivation and PA enjoyment in adults with CF, after adjusting for CFTR modulator therapy status and sex.

methodsA cross-sectional study was conducted at a specialised CF centre (N = 200). Participants completed validated questionnaires assessing motivational regulation (Behavioural Regulation Questionnaire-2, BREQ-2) and PA enjoyment (Physical Activity Enjoyment Scale, PACES). Clinical data, including the ppFEV₁, were obtained from medical records. Multivariate general linear models (GLM), partial correlations, and hierarchical regression analyses were utilised.

resultsCross-sectional analyses showed that ppFEV₁ was independently associated with intrinsic motivation (β = .233, p < .001), the relative autonomy index (RAI) (β = .203, p = .004) and the PACES total score (β = .201, p = .004). After CFTR modulator therapy status and sex were accounted for, the additional variance explained by the ppFEV₁ was statistically significant but modest (ΔR

conclusionsAlthough ppFEV₁ showed small, independent associations with autonomous motivational regulation and PA enjoyment in adults with CF, lung function should not be used as a proxy for motivational support needs. To provide person-centred, SDT-informed support that encourages sustained participation in PA, the motivational regulation and enjoyment of PA should be assessed directly in adults with CF.

Indexed as

Cystic FibrosisExerciseMotivationAdolescentAdultCross-Sectional StudiesFemaleForced Expiratory VolumeHumansLinear ModelsMaleSurveys and QuestionnairesYoung AdultAutonomous motivationCFTR modulator therapyCystic fibrosisPhysical activity enjoymentPulmonary functionSelf-determination theorySex

Identifiers

PMID42706523
PMCPMC13548599

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.