Evidence map›Paper›PMID 42706427›Full record

ArticleNature plants2026

Cell-based CRISPRa screen identifies a papillae-specific receptor kinase mediating broad-spectrum fungal resistance in rice.

Feng-Zhu Wang, Ying Bao, Jiehua Qiu, Mo-Xian Chen, He Jiang, Zhenxiang Li, Xiangyu Xiong, Xianya Jiang, Yanjun Kou, Jian-Feng Li

Abstract read
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In one paragraph

Article in Nature plants, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Feng-Zhu Wang *State Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory of Plant Stress Biology, MOE Key Laboratory of Gene Function and Regulation, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
Ying Bao *State Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory of Plant Stress Biology, MOE Key Laboratory of Gene Function and Regulation, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
Jiehua QiuState Key Laboratory of Rice Biology and Breeding, China National Rice Research Institute, Hangzhou, China.
Mo-Xian ChenState Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory of Plant Stress Biology, MOE Key Laboratory of Gene Function and Regulation, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.ORCID http://orcid.org/0000-0003-4538-5533
He JiangGuangdong Provincial Key Laboratory of Magnetoelectric Physics and Devices, School of Physics, Sun Yat-sen University, Guangzhou, China.
Zhenxiang LiState Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory of Plant Stress Biology, MOE Key Laboratory of Gene Function and Regulation, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.ORCID http://orcid.org/0000-0002-4800-2668
Xiangyu XiongState Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory of Plant Stress Biology, MOE Key Laboratory of Gene Function and Regulation, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
Xianya JiangYangjiang Institute of Agricultural Sciences, Yangjiang, China.
Yanjun KouState Key Laboratory of Rice Biology and Breeding, China National Rice Research Institute, Hangzhou, China. kouyanjun@caas.cn.ORCID http://orcid.org/0000-0003-4189-0962
Jian-Feng LiState Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory of Plant Stress Biology, MOE Key Laboratory of Gene Function and Regulation, School of Life Sciences, Sun Yat-sen University, Guangzhou, China. lijfeng3@mail.sysu.edu.cn.ORCID http://orcid.org/0000-0001-5783-0804

Funding

National Natural Science Foundation of China (National Science Foundation of China) 32125004National Natural Science Foundation of China (National Science Foundation of China) 32370294Natural Science Foundation of Zhejiang Province (Zhejiang Provincial Natural Science Foundation) LR24C140001
6 · The paper itself

Abstract

Gain-of-function screens enable the discovery of gene functions and candidate targets for molecular breeding. Here we developed a protoplast-based dCas9-TV-mediated CRISPR activation screen in rice and identified OsTV1, an epidermal papillae-specific receptor kinase, as a positive regulator of fungal resistance. OsTV1 overexpression enhanced silicon deposition, leaf rigidity and basal defence gene expression, conferring broad-spectrum fungal resistance without compromising growth. This study establishes a high-throughput gain-of-function screen adaptable for investigating diverse cellular processes in plants and provides insights into the roles of silicon in rice defence.

Identifiers

PMID42706427

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