Evidence map›Paper›PMID 42706032›Full record

ReviewZhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology2026

[Alcohol liver disease: immunoregulatory mechanisms and precision therapeutic targets].

H Y Shen, L M Wei, L Zuo, H Wang

Abstract readReviewEnglish Abstract
In one paragraph

Review in Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

H Y ShenDepartment of Oncology, the First Affiliated Hospital of Anhui Medical University, Hefei 230022, China Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Hefei 230032, China Key Laboratory of Anti-inflammatory and Immune Medicine (Anhui Medical University), Ministry of Education, Hefei 230032, China Innovation and Entrepreneurship Laboratory for College Students, Anhui Medical University, Hefei 230032, China.
L M WeiDepartment of Oncology, the First Affiliated Hospital of Anhui Medical University, Hefei 230022, China Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Hefei 230032, China Key Laboratory of Anti-inflammatory and Immune Medicine (Anhui Medical University), Ministry of Education, Hefei 230032, China Innovation and Entrepreneurship Laboratory for College Students, Anhui Medical University, Hefei 230032, China.
L ZuoKey Laboratory of Anti-inflammatory and Immune Medicine (Anhui Medical University), Ministry of Education, Hefei 230032, China Innovation and Entrepreneurship Laboratory for College Students, Anhui Medical University, Hefei 230032, China Department of Biochemistry, School of Basic Medical Science, Anhui Medical University, Hefei 230032, China.
H WangDepartment of Oncology, the First Affiliated Hospital of Anhui Medical University, Hefei 230022, China Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Hefei 230032, China Key Laboratory of Anti-inflammatory and Immune Medicine (Anhui Medical University), Ministry of Education, Hefei 230032, China.

Funding

National Key Research and Development Program of China 2023YFA1800800National Natural Science Foundation of China 82225008National Science and Technology Major Project 2024ZD0530600
6 · The paper itself

Abstract

Alcohol liver disease (ALD) represents a major health challenge worldwide, with particularly high mortality in severe alcohol-associated hepatitis. Inflammation plays a central role in ALD progression, and immune cells along with their inflammatory mediators contribute to disease development through actions in both the liver and extrahepatic organs. Currently, there is a lack of targeted therapies that can effectively block chronic ALD progression or intervene in alcohol-related acute liver failure. This article elucidates the core mechanisms by which immune heterogeneity drives the development and progression of ALD and influences treatment responses, summarizes current clinical research progress in anti-inflammatory therapies, and highlights promising future directions, particularly biomarker-guided precision therapy.

Indexed as

Liver Diseases, AlcoholicHumans

Identifiers

PMID42706032
PMCPMC13529430

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.