ArticleDiabetes/metabolism research and reviews2026
Redefining Obesity Risk for Heart Failure: Incorporating Morbidity Into the 2024 EASO Framework Definition of Obesity.
Article in Diabetes/metabolism research and reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundConventional BMI-based obesity classification fails to capture the metabolic heterogeneity underlying obesity-related heart failure (HF) risk. We evaluated the 2024 European Association for the Study of Obesity (EASO) framework-which integrates central adiposity with medical, functional, and psychological morbidity-to refine HF risk stratification.
methodsAmong 449,550 UK Biobank participants (median follow-up 15.5 years), we applied three obesity definitions: (1) BMI ≥ 30 kg/m
resultsThe EASO framework reclassified 15.6% of conventionally overweight individuals as obese, increasing the obesity prevalence from 24.5% to 40.1%. Compared with normal-weight individuals, the EASO overweight group (BMI 25-< 30 kg/m
conclusionsThe EASO framework refines HF risk stratification by uncovering morbidity-driven vulnerability within the overweight range that BMI alone obscures. The extended framework further demonstrates that morbidity status-rather than anthropometric thresholds-is a primary modifier of HF risk across all adiposity categories, supporting a shift from purely anthropometric toward phenotype-based obesity classification in cardiovascular risk assessment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.