Evidence map›Paper›PMID 42704464›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2026

Efficacy of a 445 nm wavelength laser in the surgical treatment of chronic otitis media.

David Leffers, Zuzana Penxová, Paula Enzian, Birgit Lange, Ralf Brinkmann, Karl-Ludwig Bruchhage, Anke Leichtle

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Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

David LeffersDepartment of Otorhinolaryngology, Head and Neck Surgery, University of Luebeck, Ratzeburger Allee 160, 23538, Luebeck, Germany. David.Leffers@uksh.de.ORCID http://orcid.org/0000-0003-3549-1535
Zuzana PenxováDepartment of Otorhinolaryngology, Head and Neck Surgery, University of Luebeck, Ratzeburger Allee 160, 23538, Luebeck, Germany.ORCID http://orcid.org/0000-0001-5673-3498
Paula EnzianMedical Laser Center Luebeck, Luebeck, Germany.ORCID http://orcid.org/0009-0007-4600-695X
Birgit LangeMedical Laser Center Luebeck, Luebeck, Germany.ORCID http://orcid.org/0000-0002-4782-0810
Ralf BrinkmannMedical Laser Center Luebeck, Luebeck, Germany.ORCID http://orcid.org/0000-0002-0445-8102
Karl-Ludwig BruchhageDepartment of Otorhinolaryngology, Head and Neck Surgery, University of Luebeck, Ratzeburger Allee 160, 23538, Luebeck, Germany.
Anke LeichtleDepartment of Otorhinolaryngology, Head and Neck Surgery, University of Luebeck, Ratzeburger Allee 160, 23538, Luebeck, Germany.ORCID http://orcid.org/0000-0001-8067-4299

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

hypothesisLaser-assisted middle ear surgery using a blue wavelength laser is a sufficient treatment option for chronic otitis media.

introductionDefinitive treatment of chronic otitis media necessitates complete removal of all sites of inflammation. Laser-based surgical techniques have demonstrated promise for achieving thorough resection while preserving auditory function. This study examines the clinical outcomes associated with the use of a 445 nm diode laser, specifically regarding recurrence rates and postoperative hearing restoration in patients with chronic otitis media.

methodsA cohort of 53 patients (21 Laser respectively 32 microsurgical) undergoing microscopic middle ear surgery for chronic otitis media at the Department of Ear, Nose and Throat Medicine, University of Lübeck, was included based on guideline-driven indications. The surgical intervention employed a fiber-guided approach using a commercial 445 nm wavelength diode laser for tissue ablation, operated in pulse mode with a laser peak power of up to 4 Watt, compared to conventional microsurgical techniques. Retrospective analysis was performed to evaluate recurrence and audiometric outcomes, assessed via pure-tone averages for air and bone conduction thresholds.

resultsSix months postoperatively, patients in the diode laser cohort exhibited a significant improvement in hearing outcomes compared to those treated with conventional microsurgical techniques (median AC-PTA improved from 45.36 dB to 30.67 dB in the laser group versus 43.48 dB to 44.45 dB in the microsurgical group; p = 0.0163). All documented recurrences occurred exclusively within the microsurgical treatment group.

conclusionBlue laser-assisted middle ear surgery represents a safe and efficacious modality for the management of chronic otitis media.

Indexed as

Blue laserDiode laserOssicular preservationOtitis media

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.