Evidence map›Paper›PMID 42704410›Full record

ArticleJournal of thrombosis and thrombolysis2026

Dabigatran use and cerebrovascular event risk across body mass index in atrial fibrillation: a real-world nested case-control study.

Karim M Mahawish, Valery Feigin, P Alan Barber, Derrick A Bennett, Rita Krishnamurthi, Harvey D White

Abstract read
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In one paragraph

Article in Journal of thrombosis and thrombolysis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Karim M MahawishStroke Department, Adult Rehabilitation & Health of Older People, Health New Zealand - Te Whatu Ora Counties Manukau, 100 Hospital Road, Otahuhu, Auckland, 2025, New Zealand. tyj9598@autuni.ac.nz.ORCID http://orcid.org/0000-0003-2256-6470
Valery FeiginNational Institute for Stroke and Applied Neurosciences, School of Community & Public Health, Auckland University of Technology, 90 Akoranga Drive, Northcote, Auckland, 0627, New Zealand.ORCID http://orcid.org/0000-0002-6372-1740
P Alan BarberDepartment of Medicine, University of Auckland Faculty of Medical and Health Sciences, 85 Park Road, Grafton, Auckland, 1023, New Zealand.ORCID http://orcid.org/0000-0003-2469-9023
Derrick A BennettClinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, Big Data Institute, University of Oxford, Old Road Campus, Oxford, United Kingdom.ORCID http://orcid.org/0000-0002-9170-8447
Rita KrishnamurthiNational Institute for Stroke and Applied Neurosciences, School of Community & Public Health, Auckland University of Technology, 90 Akoranga Drive, Northcote, Auckland, 0627, New Zealand.ORCID http://orcid.org/0000-0003-0869-2083
Harvey D WhiteGreen Lane Cardiovascular Service, Health New Zealand - Te Whatu Ora, Te Toka Tumai, Auckland City Hospital, Park Road, Grafton, Auckland, 1051, New Zealand.ORCID http://orcid.org/0000-0001-7712-6750

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dabigatran is widely used for stroke prevention in atrial fibrillation (AF), but concerns remain regarding its effectiveness in patients with Class III obesity ( BMI ≥40 kg/m2.) We evaluated the association between dabigatran use in patients with AF and ischaemic stroke (IS) or transient ischaemic attack (TIA) across body mass index (BMI) categories in a multiethnic New Zealand population. In this retrospective nested case-control study, cases with incident IS/TIA were identified from the fifth Auckland Regional Community Stroke Study (1st September 2020-31st August 2021), and event-free controls were randomly selected from the National Minimum Dataset. Multivariable logistic regression was used to estimate adjusted odds ratios (aORs) for IS/TIA, and effect modification by BMI catergory (< 30, 30-39.9, ≥40 kg/m

Indexed as

Atrial fibrillationDabigatranIschaemic strokeObesityTransient ischaemic attack

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.