ArticleRadiology and oncology2026
Luciferase-induced immune activation prevents orthotopic K7M2luc osteosarcoma establishment in BALB/c mice.
Article in Radiology and oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundUse of murine orthotopic tumor models dictates utilization of luciferase-expressing cells for MATERIALS AND
methodsWe transduced K7M2 cells wild-type (wt) with luciferase gene and evaluated their growth
resultsAll investigated cell lines had a comparative doubling time
conclusionsThese findings indicate that luciferase activates cytotoxic T-cell responses capable of eliminating implanted cells. Tumor establishment was restored in immunodeficient mice lacking CD8
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