ArticleeLife2026
Preserved cerebellar functions despite structural degeneration in older adults.
Article in eLife, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Age-related changes in proprioception are of limited size, outcome-dependent and task-dependent.GeroScience · 2026Article
- Adults up to 80 years old maintain effective movement planning when facing complex body dynamics.GeroScience · 2026Article
- Article
- Sensorimotor Adaptation to a Nonuniform Formant Perturbation Is Preserved in Healthy Aging.Journal of speech, language, and hearing research : JSLHR · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Aging is frequently perceived negatively due to its association with declines in brain and motor function yet not all aspects of brain function are equally affected. The cerebellum, a brain region closely linked to motor control, undergoes clear structural changes with age, but the impact of this degeneration on cerebellar function remains debated. The present study thoroughly investigates the impact of age on cerebellar function by measuring cerebellar motor and cognitive performance across the lifespan in 50 young adults (20-35 years), 80 older adults (55-70 years), and 30 older-old adults (over 80 years). Participants completed a test battery comprising seven motor control tasks and one cognitive task each designed to probe both cerebellar-specific and general sensorimotor function. Our results revealed that, despite age-related changes in cerebellar structure, cerebellar-specific functions remained intact in older adults compared to young adults, even among those above 80 years old. In contrast, general sensorimotor measures showed a clear pattern of decline with age. Together, these findings indicate that cerebellar function is largely preserved despite pronounced structural degeneration, providing compelling evidence for the cerebellum's remarkable functional resilience.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.