Evidence map›Paper›PMID 42703850›Full record

ArticleAnnals of rehabilitation medicine2026

Association of Daily Activity Regularity With Functional Recovery in Patients With Stroke and Spinal Cord Injury: A Prospective Actigraphy Study.

Yu-Hsuan Lin, Chen Lin, Chueh-Hung Wu, Hsiang-Chih Chang, Huey-Wen Liang, Shao-Yu Chen, Kuan-Lin Sung, Wei-Chen Hsu

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Article in Annals of rehabilitation medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

8 authors.

Yu-Hsuan LinInstitute of Population Health Sciences, National Health Research Institutes, Miaoli County, Taiwan.
Chen LinDepartment of Biomedical Sciences and Engineering, National Central University, Taoyuan City, Taiwan.
Chueh-Hung WuDepartment of Physical Medicine and Rehabilitation, College of Medicine, National Taiwan University, Taipei, Taiwan.
Hsiang-Chih ChangInstitute of Population Health Sciences, National Health Research Institutes, Miaoli County, Taiwan.
Huey-Wen LiangDepartment of Physical Medicine and Rehabilitation, College of Medicine, National Taiwan University, Taipei, Taiwan. lianghw@ntu.edu.tw.
Shao-Yu ChenDepartment of Physical Medicine and Rehabilitation, National Taiwan University Hospital, Taipei, Taiwan.
Kuan-Lin SungDepartment of Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.
Wei-Chen HsuDepartment of Physical Medicine and Rehabilitation, National Taiwan University Hospital Hsin-Chu Branch, Hsinchu, Taiwan.

Funding

National Health Research Institutes 112-HR0008National Health Research Institutes 12A1-PHSP05-014National Taiwan University Hospital Hsin-Chu Branch
6 · The paper itself

Abstract

Objective: To determine whether the stability of daily physical activity, quantified by interdaily stability (IS), is associated with activities of daily living (ADL) recovery during inpatient neurorehabilitation, independent of overall activity level, we examined the association between physical activity stability and ADL recovery.

methodsThis prospective study recruited 161 patients with stroke or spinal cord injury (mean age: 62.4±14.8 years; 42% female) from two hospitals. Physical activity was assessed using actigraphy for seven days after admission. IS represented activity regularity, and M10 the total activity volume during the most active 10-hour period. ADL was evaluated using the Barthel Index (BI) (baseline BI=32.5±22.9; discharge BI=61.1±28.6). Multiple linear regression analyses examined IS, M10, and ADL recovery, adjusting for baseline BI, age, sex, hospital stay, days from onset to rehabilitation admission, and diagnosis group.

resultsHigher IS during the first week after admission was significantly associated with better ADL recovery at discharge after controlling for all covariates (B=30.86, p=0.005). In contrast, total physical activity (M10) was not significantly associated with ADL recovery (B=-0.11, p=0.313). Younger age, lower baseline BI, longer length of stay, and shorter onset-to-admission time were also associated with greater ADL recovery. Conclusion: Greater activity stability was associated with greater ADL improvement in patients with stroke, but not in those with spinal cord injury. IS may be a clinically relevant behavioral marker during inpatient rehabilitation, although its causal role remains to be established.

Indexed as

ActigraphyActivities of daily livingActivity cyclesCircadian rhythmNeurological rehabilitation

Identifiers

PMID42703850
PMCPMC13554917

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