Evidence map›Paper›PMID 42703848›Full record

ArticleAnnals of rehabilitation medicine2026

Immediate Effects of Manual Muscle Stretching on Respiratory Capacity, Heart Rate Variability, and Diaphragmatic Function in Patients With COPD.

Hsin-Lun Yang, Jian-Cheng Peng, Yu-Ting Huang, Hui-Ching Cheng, Ching-Hsia Hung, Chiung-Zuei Chen, Sheng-Yuan Wang, Chin-Wei Kuo, Kun-Ling Tsai

Abstract read
In one paragraph

Article in Annals of rehabilitation medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Hsin-Lun YangInstitute of Allied Health Sciences, College of Medicine, National Cheng Kung University, Tainan City, Taiwan.
Jian-Cheng PengDepartment of Physical Therapy, College of Medicine, Tzu Chi University, Hualien, Taiwan.
Yu-Ting HuangInstitute of Allied Health Sciences, College of Medicine, National Cheng Kung University, Tainan City, Taiwan.
Hui-Ching ChengInstitute of Allied Health Sciences, College of Medicine, National Cheng Kung University, Tainan City, Taiwan.
Ching-Hsia HungInstitute of Allied Health Sciences, College of Medicine, National Cheng Kung University, Tainan City, Taiwan.
Chiung-Zuei ChenDepartment of Physical Therapy, College of Medicine, National Cheng Kung University, Tainan City, Taiwan.
Sheng-Yuan WangDepartment of Physical Therapy, College of Medicine, National Cheng Kung University, Tainan City, Taiwan.
Chin-Wei KuoDepartment of Physical Therapy, College of Medicine, National Cheng Kung University, Tainan City, Taiwan. kbh557@gmail.com.
Kun-Ling TsaiInstitute of Allied Health Sciences, College of Medicine, National Cheng Kung University, Tainan City, Taiwan. kunlingtsai@mail.ncku.edu.tw.

Funding

Ministry of Science and Technology, Taiwan MOST-106-2314-B-006-023National Cheng Kung University Hospital NCKUH-11404065National Science and Technology Council NSTC 113-2410-H-024-012-MY2
6 · The paper itself

Abstract

Objective: To investigate the acute physiological responses following a single session of manual muscle stretching in patients with moderate to severe chronic obstructive pulmonary disease (COPD).

methodsA single-group pre-post design was used. Nineteen participants with moderate to severe COPD received one session of manual stretching, incorporating passive stretching and muscle energy techniques targeting the anterior scalene, upper trapezius, pectoralis, and diaphragm muscles. Primary outcomes included spirometry values, static lung volumes, heart rate variability (HRV), and diaphragmatic ultrasound. Secondary outcomes included respiratory muscle strength, upper limb flexibility, and symptom scores.

resultsFollowing the intervention, participants exhibited a significant increase in expiratory reserve volume and diaphragmatic mobility, accompanied by a decrease in resting heart rate. HRV parameters (SDNN, RMSSD, LF, HF, and TP) showed significant changes following the intervention. Maximal inspiratory pressure increased from 76±47% to 85±51%, and maximal expiratory pressure increased from 55±30% to 67±34%, along with enhanced upper limb flexibility. Chest tightness, as assessed by the COPD Assessment Test, was significantly reduced. However, no significant changes were observed in spirometry values (FEV1, FVC, FEV1/FVC), other static lung volumes (TV, IRV, IC, VC), standardized HRV indices (HFnu, LFnu, LF/HF), or modified Medical Research Council scores. Conclusion: A single session of manual muscle stretching may be associated with immediate changes in respiratory mechanics, autonomic function, and symptom perception in patients with COPD.

Indexed as

Chronic obstructive pulmonary diseaseDiaphragmatic functionHeart rate variabilityLung functionManual muscle stretching

Identifiers

PMID42703848
PMCPMC13554918

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.