ReviewInternational journal of chronic obstructive pulmonary disease2026
Global Research Landscape and Clinical Hotspots in COPD-OSA Overlap Syndrome: A Bibliometric and Visualization Analysis.
Review in International journal of chronic obstructive pulmonary disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: This study systematically depicts the global research landscape, knowledge base, and thematic evolution of chronic obstructive pulmonary disease combined with obstructive sleep apnea overlap syndrome (COPD-OSA overlap syndrome), providing a reference for subsequent research and clinical translation. Methods: Relevant literature published between 2000 and 2025 was retrieved from the Web of Science Core Collection, Scopus, and PubMed databases. Records from Web of Science and Scopus were merged and deduplicated to construct the primary bibliometric dataset, while PubMed was analyzed separately as a supplementary source for cross-database comparison using keywords and MeSH terms. Bibliometrix, VOSviewer, and CiteSpace were used to analyze research output, collaboration networks, core sources, co-citation structure, and research hotspots. A latent Dirichlet allocation (LDA) model was applied to identify latent topics and their temporal trends. Results: The primary dataset included 1239 publications, with an average annual growth rate of 20.62%; publication volume increased markedly after 2017. The United States, China, and Italy ranked highest in publication count, yet the overall international co-authorship rate was only 6.3%. The field's knowledge base centers on nocturnal hypoxemia, cardiovascular outcomes, acute exacerbations, and positive airway pressure therapy. The LDA model identified 10 latent topics, with two showing significant upward trends (COVID-19 with OSA; acute cardiovascular events and adipose tissue) and one showing a downward trend (anthropometry and lung function parameters). The 274 PubMed-included articles complemented cross-database comparisons and indicated growing attention to cognitive function, oxygen saturation, and digital screening. Conclusion: Research on COPD-OSA overlap syndrome is shifting from describing disease coexistence toward complex multimorbidity, risk stratification, and individualized management. However, international collaboration and high-level clinical evidence remain insufficient. Future work should standardize case definitions, establish multicenter longitudinal cohorts, and conduct phenotype-based treatment studies.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.