ArticleJournal of hepatocellular carcinoma2026
Hepatocellular Carcinoma at a Center of Clinical Excellence in Colombia: A Real-World Cohort Study of Clinical Characteristics, Treatment Trajectories, and Survival.
Article in Journal of hepatocellular carcinoma, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: Hepatocellular carcinoma (HCC) is the sixth most common malignancy worldwide. In middle-income settings, fragmentation of care may delay diagnosis and limit access to timely treatment. This study aimed to describe the sociodemographic and clinical characteristics, treatment patterns, and overall survival of patients with HCC managed at a Center of Clinical Excellence (CCE). Patients and Methods: We conducted a retrospective descriptive cohort study of adults (≥18 years) with HCC managed at a CCE between September 2022 and December 2025. Baseline variables included etiology, comorbidities, Child-Pugh class, Model for End-Stage Liver Disease (MELD) score, Barcelona Clinic Liver Cancer (BCLC) stage, and alpha-fetoprotein (AFP) levels. Treatment strategies and clinical course, including stage migration, liver transplantation, and death, were described. Overall survival was estimated using the Kaplan-Meier method. Results: A total of 134 patients were included. Median age was 67.93 years (IQR 63.12-72.59) and 61.19% were men. The most common underlying etiology was metabolic dysfunction-associated steatotic liver disease (MASLD) (34.38%). Most patients were diagnosed at early BCLC stages 0/A (64.18%; n = 86). Ablation and transarterial chemoembolization were the most frequently used treatments, and liver transplantation was performed in 9.70% of patients. After a median follow-up of 21 months, median overall survival was not reached; estimated survival was 93.8% at 1 year and 80.0% at 3 years. Conclusion: In this retrospective cohort managed at a CCE, MASLD was the most frequent underlying etiology, and patients were diagnosed at early stages BCLC stages 0/A. Treatment patterns were dominated by locoregional therapies, and median overall survival was not reached during the available follow-up period. These findings provide real-world data on HCC care in a middle-income setting and highlight the clinical relevance of describing treatment trajectories and survival within structured multidisciplinary care programs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.