ArticleJournal of gastrointestinal oncology2026
Prediction of histological response by PET-CT after 2 weeks of neoadjuvant chemo-radiotherapy for rectal cancer: a prospective clinical trial.
Article in Journal of gastrointestinal oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
9 authors.
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Abstract
Background: Early prediction of pathological response to neoadjuvant chemoradiotherapy (nCRT) in locally advanced rectal cancer (LARC) may help guide individualized treatment strategies. This prospective clinical trial aimed to evaluate whether interim Methods: Twenty-one LARC patients receiving nCRT followed by surgery were included. Results: No significant differences in ΔSUV-mean%, ΔSUV-max%, and ΔMTV% were found between pCR and non-pCR groups or between TRG I-II and TRG III-V groups. Absolute SUV-mean and SUV-max values at baseline, and SUV-max and MTV values at 2 weeks, differed significantly between pCR and non-pCR groups. ROC analyses demonstrated discriminatory ability for predicting pCR, with area under the curve (AUC) values of 0.79-0.82. Conclusions: Early metabolic response after 2 weeks of nCRT did not correlate with pCR or TRG in LARC. Absolute SUV-mean and SUV-max values at baseline and absolute SUV-max and MTV values at 2 weeks showed predictive value for pCR.
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