ArticleJournal of gastrointestinal oncology2026
Relationships among slow diffusion coefficient and diffusion-derived 'vessel density' signal features, Gadoxetate delayed enhancement, tumor size, tumor grading, and patient survival: an exploratory study of mass-forming intrahepatic cholangiocarcinoma.
Article in Journal of gastrointestinal oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Classification of hepatocellular carcinoma Ki-67 expression status by a simple combination of magnetic resonance slow diffusion coefficient (SDC) and apparent diffusion coefficient (ADC): initial promising results.Quantitative imaging in medicine and surgery · 2026Article
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7 authors.
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Abstract
Background: Intrahepatic cholangiocarcinoma (ICC) literature suggests that hypervascularity on arterial contrast agent enhancement (CE) is associated with better prognosis, while rich stroma is associated with poorer prognosis. This exploratory study evaluates the relationships among slow diffusion coefficient (SDC) and diffusion-derived 'vessel density' (DDVD) signal features, Gadoxetate delayed enhancement, and survival in patients with mass-forming ICC. An ICC with higher SDC may be associated with potentially better patient survival due to less stromal fibrosis. Methods: Data were prospectively acquired in two centers [Center 1 (Sun Yat-Sen Memorial Hospital): ICC 21 cases; Center 2 (Fifth Affiliated Hospital of Anhui Medical University): ICC 3 cases]. SDC maps were derived with Results: Tumor aggressiveness was negatively correlated with quantitative '% delay CE' (Spearman Conclusions: ICCs with higher SDC score (≥2.5) and small/intermediate presenting tumor size (<4,000 cm
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