Evidence map›Paper›PMID 42703453›Full record

ArticleJournal of gastrointestinal oncology2026

Association of ctDNA

Manuel Valladares-Ayerbes, Pilar García Alfonso, Volker Heinemann, Paolo Manca, Sebastian Stintzing, Filipo Pietrantonio, Clara Montagut, Maria José Safont Aguilera, Joan Maurel, Encarna González Flores and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of gastrointestinal oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Manuel Valladares-AyerbesMedical Oncology Department, Hospital Universitario Virgen del Rocio (HUVR), Institute of Biomedicine of Seville (IBiS), Seville, Spain.
Pilar García AlfonsoMedical Oncology Service, Medical Oncology Service, General University Hospital Gregorio Marañón, Gregorio Marañón Health Research Institute (IiSGM), Universidad Complutense, Madrid, Spain.
Volker HeinemannDepartment of Hematology/Oncology, LMU Klinikum, University of Munich, Comprehensive Cancer Center, Munich, Germany.
Paolo MancaMedical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Sebastian StintzingDepartment of Hematology, Oncology, and Cancer Immunology (CCM) of Charité - Universitaetsmedizin Berlin, Germany.
Filipo PietrantonioMedical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Clara MontagutMedical Oncology Department, Hospital del Mar, Colorectal Cancer Precision Medicine Group, CIBERONC, Hospital del Mar Research Institute.
Maria José Safont AguileraMedical Oncology, General University Hospital Consortium of Valencia, Valencia University, Valencia, Spain.
Joan MaurelCentro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.
Encarna González FloresMedical Oncology, Hospital Virgen de las Nieves, Instituto de Investigación Biosanitaria ibs, Granada, Spain.
Joana VidalMedical Oncology Department, Hospital del Mar, Colorectal Cancer Precision Medicine Group, CIBERONC, Hospital del Mar Research Institute.
Vincenzo FormicaMedical Oncology Unit, Department of Internal Medicine, 'Tor Vergata' University Hospital, Rome, Italy.
Montse Sabaté-PinaTFS HealthScience, Barcelona, Spain.
Verónica Alfonso-GonzálezTFS HealthScience, Barcelona, Spain.
Gerard Prat-LlorensAMGEN S.A., Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Monitoring

Indexed as

anti-epidermal growth factor receptor (anti-EGFR)Circulating tumor DNA (ctDNA)colorectal cancerRAS

Identifiers

PMID42703453
PMCPMC13546528

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.