ArticleJournal of gastrointestinal oncology2026
A study on screening of postoperative chemotherapy beneficial populations in stage II colorectal cancer based on diffusion weighted imaging and
Article in Journal of gastrointestinal oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Stage II colorectal cancer (CRC) shows marked prognostic heterogeneity, yet existing single serum or imaging markers are insufficient for reliable high‑risk patient stratification. This study aimed to investigate the value of diffusion-weighted imaging (DWI), fluorine-18fluorodeoxyglucose positron emission tomography/computed tomography ( Methods: A total of 106 patients with pathologically confirmed CRC were retrospectively enrolled and divided into high-risk stage II and non-high-risk stage II groups according to high-risk factors. Clinical data were collected, and apparent diffusion coefficient (ADC) values and maximum standardized uptake value (SUVmax) of lesions were measured in both groups. The consistency of each parameter was assessed using the intraclass correlation coefficient (ICC). Independent-samples Results: ADC values were significantly lower in the high-risk stage II CRC group than in the non-high-risk group (P<0.05), while SUVmax and CEA levels were significantly higher (P<0.05). The combined model of ADC value, SUVmax, and CEA showed better diagnostic performance than any single parameter (P<0.05). A strong negative correlation between SUVmax and ADC value was observed in both the high-risk group r=-0.638 and the non-high-risk group r=-0.777. Conclusions: The combination of DWI,
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