Evidence map›Paper›PMID 42703276›Full record

ArticleOrthopaedic journal of sports medicine2026

Personalizing the Quadriceps Tendon Graft in Anterior Cruciate Ligament Reconstruction: A Novel, Continuous Method to Predict Graft Size Using Preoperative MRI.

Zi Qiang Glen Liau, Bryan Khoo, Hubert Tuyishime, Matthew Song Peng Ng, Alexander Shao-Rong Pang, James Hoi Po Hui, Kevin Shea

Abstract read
In one paragraph

Article in Orthopaedic journal of sports medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

7 authors.

Zi Qiang Glen LiauDepartment of Orthopedic Surgery, National University Hospital, Singapore, Singapore.ORCID https://orcid.org/0000-0002-0498-9237
Bryan KhooDepartment of Pediatric Orthopedics, Stanford University, California, USA.ORCID https://orcid.org/0009-0000-1528-9829
Hubert TuyishimeSchool of Medicine, Stanford University, California, USA.ORCID https://orcid.org/0000-0001-8717-4692
Matthew Song Peng NgDepartment of Orthopedic Surgery, National University Hospital, Singapore, Singapore.ORCID https://orcid.org/0000-0002-7282-9243
Alexander Shao-Rong PangDepartment of Orthopedic Surgery, National University Hospital, Singapore, Singapore.ORCID https://orcid.org/0009-0003-3195-5491
James Hoi Po HuiDepartment of Orthopedic Surgery, National University Hospital, Singapore, Singapore.ORCID https://orcid.org/0000-0002-1130-4558
Kevin SheaDepartment of Pediatric Orthopedics, Stanford University, California, USA.ORCID https://orcid.org/0000-0002-4160-0163

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The quadriceps tendon (QT) graft is increasingly popular in primary anterior cruciate ligament reconstruction (ACLR). However, postoperative quadriceps strength can be significantly weakened after use of a QT graft, compared to using hamstring tendon or bone-patellar tendon-bone grafts. There currently exists no continuous method to predict QT graft size based on preoperative magnetic resonance imaging (MRI) measurements; only dichotomous methods exist at limited cutoff values. Purpose: To (1) assess the accuracy of preoperative MRI QT thickness in predicting graft size dichotomously (<10 mm vs ≥10 mm), (2) assess the accuracy of the formula 2 ×√( Study Design: Cross-sectional study; Level of evidence, 3. Methods: This is a retrospective review of 130 patients who underwent primary ACLR with full-thickness QT autografts at a single tertiary institution from January 1, 2022, to July 17, 2025. A novel, reproducible method to measure QT thickness on the MRI sagittal view at the most proximal patellar attachment site was developed. Two blinded reviewers independently measured QT thickness. Receiver operating characteristic (ROC) analysis was performed to determine the optimal threshold for predicting a final graft diameter <10 mm, with area under the curve (AUC) as the primary measure of discriminative ability. Sensitivity and specificity at the optimal threshold were additionally reported given their direct clinical relevance to intraoperative decision-making at a fixed cutoff. Results: The mean age was 16.4 years (95% CI, 15.9-16.9 years), with 59 females and 71 males. ROC analysis identified a preoperative QT thickness <8.3 mm as the optimal threshold for predicting a final graft diameter <10 mm, with an AUC of 0.818, a sensitivity of 98.2%, and a specificity of 39.1%. The authors applied the formula 2 ×√( Conclusion: The authors present a novel, numerically continuous way of predicting harvested quadriceps graft size. A preoperative QT thickness <8.3 mm is 98.2% sensitive and 39.1% specific in predicting a final graft diameter <10 mm. Personalizing the width of the harvested QT according to patient's tendon thickness and surgeon's desired graft size may be considered to minimize unnecessary over- or underharvesting of QT in the future.

Indexed as

anterior cruciate ligamentgraft personalizationkneeMRIpredictionquadriceps tendon graft

Identifiers

PMID42703276
PMCPMC13546423

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.