ArticleWorld journal of urology2026
Segmental versus non-segmental inferior vena cava resection during robot-assisted radical nephrectomy and thrombectomy: an overlap-weighted analysis.
Article in World journal of urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeIVC segmental resection (SR) during robot-assisted radical nephrectomy and IVC thrombectomy (RARN-IVCT) is selected for wall invasion, occlusion, and collateral outflow, making direct comparison with non-segmental resection (NSR) biased. We compared the perioperative and renal safety of SR versus NSR in the overlap population.
methodsRetrospective single-center cohort at Peking University Third Hospital (2014-2025): 120 patients with RCC and Mayo level II-IV IVC thrombus undergoing RARN-IVCT, including 45 SR and 75 NSR. Overlap weighting balanced baseline variables. Primary outcomes were AKI, ΔSCr, and ΔeGFR; secondary outcomes were complications and hospital stay, with OS assessed exploratorily.
resultsAfter weighting, no statistically significant differences were observed in AKI, ΔSCr, ΔeGFR, complications, hospital stay, or OS. SR had lower RBC transfusion volume (mean difference - 249.63 mL, 95% CI - 443.20 to - 56.05; P = 0.011). SR met non-inferiority/equivalence for hospital stay and pneumonia; renal non-inferiority was not established. Limitations include retrospective design, limited effective sample size, and unmeasured anatomic/hemodynamic confounding.
conclusionIn overlap patients, no statistically significant differences in renal or safety/recovery outcomes were observed, but neither renal non-inferiority nor equivalence was established. Planning should consider thrombus-wall interaction, caval patency, collateral outflow, and renal reserve.
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