Evidence map›Paper›PMID 42701738›Full record

ArticleBioinformation2026

Dentin microhardness changes and smears layer removal following conventional versus alternative irrigation regimens in root canals.

Shefali Talekar, Adiya Apon, Sarita Vikram Singh, Smitha Reddy, Prachi Kapade, Ritika Pundir, Miral Mehta

Abstract read
In one paragraph

Article in Bioinformation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shefali TalekarDepartment of Conservative Dentistry and Endodontics, Bharati Vidyapeeth Dental College and Hospital, Navi Mumbai, Maharashtra, India.
Adiya AponDepartment of Dentistry, Nagaland Institute of Medical Sciences and Research, Kohima, Nagaland, India.
Sarita Vikram SinghDepartment of Conservative Dentistry and Endodontics, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Pune, Maharashtra, India.
Smitha ReddyDepartment of Conservative Dentistry and Endodontics, Sri Sai College of Dental Surgery Vikarabad, Telangana, India.
Prachi KapadeDepartment of Oral Pathology and Microbiology, MGV's KBH Dental College and Hospital, Nashik, Maharashtra, India.
Ritika PundirDepartment of Conservative Dentistry and Endodontics, NSVK Shri Venkateshwara Dental College and Hospital, Bangalore, Karnataka, India.
Miral MehtaDepartment of Pediatric and Preventive Dentistry, Karnavati School of Dentistry, Karnavati University, Gandhinagar, Gujarat, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Effective irrigation during root canal treatment is essential for disinfection and smear layer removal, through its effects on dentin microstructure remain insufficiently explored. Therefore, it is of interest to compare the five irrigation protocols-NaOCl/EDTA, NaOCl/ citric acid, CHX/EDTA, MTAD and QMix-on dentin microhardness and smear layer removal. All experimental groups showed significant microhardness reduction compared with control, with NaOCl/EDTA causing the greatest decrease. QMix and MTAD demonstrated superior smear layer removal with moderate effects on dentin hardness, while QMix showed consistent performance across root levels. Thus, data shows the QMix and MTAD provide a balanced alternative to conventional NaOCl/EDTA, maintaining effective smear-layer removal while reducing the negative impact on dentin microhardness.

Indexed as

dentin microhardnessethylenediaminetetraacetic acid (EDTA)MTADQMixRoot canal irrigationscanning electron microscopy (SEM)smear layersodium hypochlorite

Identifiers

PMID42701738
PMCPMC13545916

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.