Evidence map›Paper›PMID 42701729›Full record

ArticleBioinformation2026

Drug utilisation and adverse drug reaction monitoring in schizophrenic patients: A tertiary care hospital study in India.

Vipin Kumar Jain, Shilpa N Kaore, Megha Jain, Vaibhav Dubey

Abstract read
In one paragraph

Article in Bioinformation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Vipin Kumar JainDepartment of Pharmacology, Chhindwara Institute of Medical Sciences, Chhindwara, Madhya Pradesh, India.
Shilpa N KaoreDepartment of Pharmacology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India.
Megha JainDepartment of Dentistry, Chhindwara Institute of Medical Sciences, Chhindwara, Madhya Pradesh, India.
Vaibhav DubeyDepartment of Psychiatry, PCMS & RC, Bhopal, Madhya Pradesh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inadequate and poorly documented data on psychotropic drug utilization in schizophrenia in India necessitates systematic evaluation of prescribing patterns and associated adverse drug reactions. This prospective observational study assessed drug utilization, prescription rationality and adverse drug reactions among schizophrenia patients attending a tertiary care psychiatric outpatient department using WHO prescribing indicators. A total of 112 prescriptions comprising 285 drugs were analyzed, with atypical antipsychotics prescribed in 87% of first-visit cases, while combination therapies and polypharmacy were frequently observed. Significant dose variations were noted in commonly used antipsychotics such as risperidone, olanzapine and aripiprazole, as well as benzodiazepines like clonazepam and lorazepam (p<0.001). Atypical antipsychotics predominated due to better tolerability and lower extrapyramidal side effects, highlighting evolving prescribing trends. Thus, structured evidence on drug utilization patterns and variability in dosing, help in optimizing rational prescribing practices in schizophrenia management.

Indexed as

adverse drug reaction (ADR)Drug utilizationschizophreniatertiary hospital

Identifiers

PMID42701729
PMCPMC13545880

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.