Evidence map›Paper›PMID 42701724›Full record

ArticleBioinformation2026

Amniotic membrane for oral surgical defect coverage: A clinical study.

Meenakshi Kothari, Satishkumar G Patil, Ashwin Shah, Udupikrishna Joshi, Chaitanya Kothari

Abstract read
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In one paragraph

Article in Bioinformation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Meenakshi KothariDepartment of Oral and Maxillofacial Surgery, H.K.E's S. Nijalingappa Institute of Dental Sciences and Research Centre, Kalaburagi, Karnataka, India.
Satishkumar G PatilDepartment of Oral and Maxillofacial Surgery, H.K.E's S. Nijalingappa Institute of Dental Sciences and Research Centre, Kalaburagi, Karnataka, India.
Ashwin ShahDepartment of Oral and Maxillofacial Surgery, H.K.E's S. Nijalingappa Institute of Dental Sciences and Research Centre, Kalaburagi, Karnataka, India.
Udupikrishna JoshiDepartment of Oral and Maxillofacial Surgery, H.K.E's S. Nijalingappa Institute of Dental Sciences and Research Centre, Kalaburagi, Karnataka, India.
Chaitanya KothariDepartment of Oral and Maxillofacial Surgery, H.K.E's S. Nijalingappa Institute of Dental Sciences and Research Centre, Kalaburagi, Karnataka, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reconstruction of oral soft-tissue defects remains limited by donor-site morbidity and inconsistent healing with currently available grafts. In this prospective interventional study, we assessed human amniotic membrane (HAM) as a biologically active scaffold in 15 patients (6 cleft alveolus, 2 oral submucous fibrosis, 7 vestibuloplasty; ages 8-65 years). HAM integrated without complications in all cases, with no necrosis, infection, or immunologic rejection; median pain (VAS) fell from 2 on day 1 to 0 by day 7 (p < 0.00001) and swelling resolved by day 7 (p < 0.00001). Epithelialization reached "good" by 1 month (p < 0.00001); mucosal suppleness remained preserved through 6 months and in OSMF cases interincisal opening improved to 35-50 mm. Thus, data shows the HAM as a safe, donor-site-sparing, clinically translatable biomaterial that accelerates healing and improves function in oral soft-tissue reconstruction.

Indexed as

Amniotic membrane (AM)cleft alveolusoral submucous fibrosisvestibuloplasty

Identifiers

PMID42701724
PMCPMC13545898

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.