Evidence map›Paper›PMID 42701719›Full record

ArticleCureus2026

Changes in Left Ventricular Afterload Following Weaning From Cardiopulmonary Bypass Proved Useful for the Anesthetic Management of Aortic Valve Replacement: A Case Report.

Keisuke Sumii, Tomohisa Tamai, Takumi Yamamoto

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Keisuke SumiiAnesthesiology, Saitama Sekishinkai Hospital, Sayama, JPN.
Tomohisa TamaiAnesthesiology, Saitama Sekishinkai Hospital, Sayama, JPN.
Takumi YamamotoCardiovascular Diseases, Saitama Sekishinkai Hospital, Sayama, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During aortic valve replacement, after weaning from the cardiopulmonary bypass (CPB), systemic vascular resistance, which constitutes the left ventricular afterload, fluctuates significantly due to systemic inflammatory responses, changes in body temperature, and the use of vasoconstrictors. Particularly in hypertrophic hearts that have adapted to increased afterload for a long time, a sudden increase in afterload following weaning from CPB carries a risk of inducing left heart failure or prosthetic valve failure. With mechanical prosthetic valves, a slight physiological regurgitation is observed during valve closure. In this case, by using pulse Doppler echocardiography and transesophageal echocardiography to monitor this physiological regurgitation in real time, we were able to rapidly assess changes in left ventricular afterload and accurately manage the administration of vasoactive agents; we therefore report on the clinical course of this case.

Indexed as

aortic valve replacementcardiopulmonary bypassmechanical valvephysiological regurgitationpressure gradient

Identifiers

PMID42701719
PMCPMC13546118

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.