ArticleBioinformation2026
Linking oral microbiome with mental health: A review.
Article in Bioinformation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
1 author.
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Abstract
The gut microbiome shapes depression and anxiety, yet the oral microbiome that seeds it daily remains overlooked. Therefore, it is of interest to review on the oral microbiome's role in the gut-brain axis. A reproducible signature emerges: enriched Prevotella with depleted Haemophilus and Rothia. Four pathways connect a dysbiotic mouth to the brain inflammation, bacterial translocation, neurotransmitter signalling and HPA-axis dysregulation. As adults see hygienists more than any other clinician, dental visits could screen, prevent and refer along this axis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.