Evidence map›Paper›PMID 42701585›Full record

ArticleBioinformation2026

Comparative efficacy and cytocompatibility of antimicrobial nanocoatings versus antibiotics on titanium dental implant surfaces.

Maitreyi Ranjan, Shailesh Jain, Nikhil Prakash, Monika Sinha, Shabnam Chaudhary, Roli Singh

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioinformation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maitreyi RanjanDepartment of Microbiology, School of Dental Sciences, Sharda University, Greater Noida, Uttar Pradesh, India.
Shailesh JainDepartment of Dentistry, GEIMS, Dehradun, Uttarakhand, India.
Nikhil PrakashDepartment of Prosthodontics, Crown and Bridge, DJ College of Dental Sciences and Research, Modinagar, Uttar Pradesh, India.
Monika SinhaDepartment of Dentistry, Private Practitioner, Flora Dental care, Bangalore, India.
Shabnam ChaudharyDepartment of Dentistry, PHC Jahu, Hamirpur, Himachal Pradesh, India.
Roli SinghDepartment of Oral and Maxillofacial Pathology and Microbiology, Visiting consultant, Gupta Dental Care, Aligarh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial colonization resulting in peri-implantitis is a significant issue in dental implantology which results in an implant failure. Therefore, it is of interest to evaluate the antimicrobial efficacy and cytocompatibility of nanoparticle-based-coatings and conventional antibiotic-coatings on the titanium dental implant surfaces were compared. The determination of the cytocompatibility between human osteoblast-like cells (MG-63) was done in terms of MTT assay, cell proliferation and adhesion. AgNP coating was found to be more effective at antimicrobial efficacy against all bacteria studied (18.6±1.4 mm with S. aureus) than gentamicin (14.2±1.1 mm) and ZnO-NP (12.8±1.3 mm). Thus, data shows the nanoparticle-based coatings especially AgNPs have better antimicrobial effects with retained biocompatibility.

Indexed as

antimicrobial coatingcytocompatibilityperi-implantitissilver nanoparticles (AgNP)Titanium dental implantszinc oxide nanoparticles (ZnO-NP)

Identifiers

PMID42701585
PMCPMC13545878

What OpenQuestion holds

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Registered trials

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