Evidence map›Paper›PMID 42701515›Full record

ArticleMolecular therapy. Oncology2026

Precision virotherapy for IDH-mutant astrocytoma.

Eleni Panagioti, Sean E Lawler, Michael B Yaffe, E Antonio Chiocca, Charles H Cook

Abstract readNews
In one paragraph

Article in Molecular therapy. Oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Eleni PanagiotiDepartment of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Sean E LawlerDepartment of Pathology and Laboratory Medicine, Legorreta Cancer Center, Brown University, Providence, RI, USA.
Michael B YaffeDepartment of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
E Antonio ChioccaHarvey Cushing Neuro-oncology Laboratories, Department of Neurosurgery, Mass General Brigham Neuroscience Institute, Harvard Medical School, Boston, MA, USA.
Charles H CookDepartment of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

Funding

The Tumor Microenvironmental Barrier to Effective Viral OncolysisP01CA163205 · NCI · OHIO STATE UNIVERSITY · PI Xiaokui Mo · 2013 to 2026
$26.0M
Understanding and Overcoming T cell Immunosuppression in GlioblastomaP01CA236749 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI E. Antonio Chiocca · 2020 to 2026
$19.5M
Preclinical Toxicity Evaluation of a Potent Oncolytic VirusU01NS061811 · NINDS · OHIO STATE UNIVERSITY · PI CHIOCCA, E. ANTONIO · 2008 to 2012
$4.6M
Protein Kinase Signaling in the Genotoxic Stress ResponseR35ES028374 · NIEHS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI YAFFE, MICHAEL B · 2017 to 2024
$3.9M
Defining the role of cytomegalovirus in glioblastoma therapiesR01CA263324 · NCI · BROWN UNIVERSITY · PI CHARLES H COOK, Sean Edward Lawler · 2022 to 2026
$3.4M
Oncolytic Virus Therapeutic Responses Occur from Changes in the Glioblastoma Immune MicroenvironmentR01NS110942 · NINDS · BRIGHAM AND WOMEN'S HOSPITAL · PI E. Antonio Chiocca, Hiroshi Nakashima · 2019 to 2026
$3.4M
NCI NIH HHS P01 CA163205NCI NIH HHS P01 CA236749NCI NIH HHS R01 CA263324NIEHS NIH HHS R35 ES028374NINDS NIH HHS R01 NS110942NINDS NIH HHS U01 NS061811
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID42701515
PMCPMC13545686

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.