ArticleQuantitative imaging in medicine and surgery2026
Clinicoradiologic features and evolutionary characteristics of pulmonary focal mucinous adenocarcinomas across different density patterns: a retrospective multi-center study.
Article in Quantitative imaging in medicine and surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Pulmonary focal mucinous adenocarcinomas (MAs) (≤3 cm) frequently present with non-specific computed tomography (CT) features, posing diagnostic difficulties. This study aimed to identify the clinicoradiologic features of pulmonary focal MAs for early diagnosis. Methods: A total of 211 patients with 211 confirmed MAs were retrospectively enrolled from two centers between November 2012 and November 2025. Thirty-one (26.5%) of 117 subsolid mucinous adenocarcinomas (SS-MAs) and 20 (21.3%) of 94 solid mucinous adenocarcinomas (S-MAs) underwent follow-up CT. The clinical data and initial and follow-up CT findings were evaluated and compared between these two subtypes to identify significant differences. Results: Both SS-MAs and S-MAs mainly distributed in the lower lobes (62.4%, 62.9%) and subpleural zones (75.2%, 76.3%) (each P>0.05). Compared to patients with S-MAs, females (74.4% Conclusions: Focal SS-MAs and S-MAs are two distinct radiologic phenotypes, and understanding their respective evolutionary characteristics is helpful for early diagnosis.
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